Vale / Cox Drugs and the Eye

Sponsored by the British Optical Association
1. Auflage 2013
ISBN: 978-1-4831-9188-1
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 134 Seiten, Web PDF

Drugs and the Eye describes the mechanism of drug action in the eye. This book is composed of 14 chapters that discuss the practical aspects of drug use, the application of first aid, emergency measures, and legal aspects of the sale and supply of drugs. Some of the topics covered in the book are the anatomy and physiology of the eye, sites receiving cholinergic innervation, drug action at the muscarinic and nicotinic receptors; definition and identification of cycloplegic drugs; mode of action of atropine; use of mydriatics; muscarinic blocking drugs; and precautions with homatropine. Other chapters examine the dynamics and structure of sympathomimetic drugs, as well as the molecular structure and mode of action of cocaine. These topics are followed by discussions on the stimulation of the parasympathetic nerve by different types of miotics and the role of anticholinesterases in the eye. The final chapters look into the use of miotics to reverse mydriasis. The book can provide useful information to ophthalmic opticians, optometrists, students, and researchers.

Autoren/Hrsg.

Vale, Janet

Cox, B.

Inhaltsverzeichnis

1;Front Cover;1
2;Drugs and the Eye: Sponsored by the British Optical Association;4
3;Copyright Page;5
4;Table of Contents;8
5;Preface;6
6;Chapter 1. Anatomy and Physiology;10
6.1;THE CILIARY MUSCLE;12
6.2;INNERVATION OF THE IRIS AND CILIARY MUSCLE;12
6.3;NEUROHUMOURAL TRANSMISSION AND THE RECEPTOR THEORY OF DRUG ACTION;16
6.4;SITES RECEIVING CHOLINERGIC INNERVATION;17
6.5;DRUG ACTION AT THE MUSCARINIC RECEPTOR;21
6.6;DRUG ACTION AT THE NICOTINIC RECEPTORS;21
6.7;SITES RECEIVING ADRENERGIC INNERVATION;22
7;Chapter 2. Factors Affecting Drug Absorption;26
8;Chapter 3. Cycloplegics;30
8.1;Atropine;30
8.2;Homatropine;39
8.3;Cyclopentolate;41
8.4;Hyoscine;43
8.5;Dibutoline;44
8.6;Oxyphenonium;45
8.7;Lachesine;45
8.8;Tropicamide;45
9;Chapter 4. Mydriatics;46
9.1;THE MUSCARINIC BLOCKING DRUGS;47
9.2;THE SYMPATHOMIMETIC DRUGS;48
10;Chapter 5. Miotics;54
10.1;DIRECT ACTING MIOTICS;54
10.2;ANTICHOLINESTERASES;58
11;Chapter 6. Local Anaesthetics;64
11.1;METHODS OF APPLICATION;64
11.2;MODE OF ACTION;66
11.3;STRUCTURE AND CHEMISTRY;69
11.4;ONSET AND DURATION OF ANAESTHESIA;72
11.5;ABSORPTION, METABOLISM AND EXCRETION;72
11.6;TOXICITY;73
12;Chapter 7. Staining Agents;78
12.1;Fluorescein;78
12.2;Rose bengal;80
13;Chapter 8. Antimicrobial Agents;82
13.1;The sulphonamides;82
13.2;Propamidine and dibromopropamidine isethionate;83
13.3;Antibiotics;84
14;Chapter 9. Solutions used in Contact Lens Work;86
14.1;Hard contact lenses;87
14.2;Soft contact lenses;91
15;Chapter 10. Decongestants, Antihistamines and Anti-Inflammatory Compounds;92
15.1;Decongestants;92
15.2;Antihistamines;93
15.3;Anti-inflammatory compounds;94
16;Chapter 11. Ocular Effects of Drugs Used Systemically;96
17;Chapter 12. First Aid and Emergency Measures used by the Ophthalmic Optician;102
17.1;Foreign bodies;102
17.2;Other injuries;103
17.3;Harmful chemical agents;103
18;Chapter 13. Formulation of Eye Preparations;106
18.1;Eye drops;106
18.2;Eye ointments;113
18.3;Eye lotions;114
19;Chapter 14. Legal Aspects of Sale and Supply of Drugs;116
19.1;Pharmacy and Poisons Act, 1933;117
19.2;The Poisons List1;118
19.3;Poisons Rules2;118
19.4;Availability of poisons to the optician;119
19.5;Poisons in Part 1 only;119
19.6;Poisons in the First Schedule to the Rules (SI);120
19.7;Poisons in the Fourth Schedule (S4);121
19.8;Misuse of Drugs Act, 1971;124
19.9;Therapeutic Substances Act (TSA), 1956;124
20;Appendix;126
20.1;Passage of drugs across the cornea;126
21;Index;130