Volcheck Clinical Allergy

Diagnosis and Management
1. Auflage 2009
ISBN: 978-1-59745-315-8
Verlag: Humana Press
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 491 Seiten

Reihe: Current Clinical Practice

Allergic diseases affect nearly one-fourth of the population and cause or contribute to significant chronic illness. Allergic diseases are common and are seen by a wide variety of health care providers. In Clinical Allergy: Diagnosis and Management, the author provides a practical clinical overview for the common disorders encountered in the specialty of Allergy. Designed to be easily readable and to provide clinically applicable information for both the nonallergist and allergist, the intent is to unravel the mystery of allergy. The introductory chapters focus on the human immune response, environmental allergens, and the different types of allergy testing. The subsequent chapters focus on the common allergic conditions seen in the office or clinic, including rhinitis and rhinosinusitis, allergic eye disease, asthma, urticaria and angioedema, atopic and contact dermatitis, drug allergy, food allergy, anaphylaxis, and stinging insect allergy. 'Cross-talk' between chapters helps show the interrelationships among the various allergic disorders. The chapters begin with a review of pathophysiologic mechanisms and then consider a clinically structured approach to diagnosis and management of the disorders. In addition to pharmacologic treatment, the importance of nonpharmacologic management and patient education is emphasized. At the end of each chapter, clinical vignettes highlight the daily management of the allergic patient. Clinical Allergy: Diagnosis and Management, provides a logical framework for the evaluation and management of allergic disorders in patients.

Autoren/Hrsg.

Volcheck, Gerald W.

Inhaltsverzeichnis

1;Clinical Allergy;2
2;Gerald W. Volcheck;4
3;Series Editor’s Introduction;7
4;Preface;8
5;Contents;9
6;Overview of the Human Immune Response;19
6.1;1.1 Introduction;19
6.2;1.2 Innate Immune System;20
6.3;1.3 Acquired Immune System;25
6.4;1.4 T- and B-Cells in the Acquired Immune Response;29
6.5;1.5 Lymphoid Tissues;38
6.6;1.6 Tolerance: Distinguishing Self from Nonself;39
6.7;1.7 Cytokines;40
6.8;1.8 Chemokines;44
6.9;1.9 Complement;46
6.10;1.10 Inflammatory Cells;46
6.11;1.11 Primary Mediators of Inflammation;48
6.12;1.12 Allergic Response to an Allergen: Summary;52
6.13;1.13 Immune-Modulating Medications in Allergic Disease;52
6.14;1.14 Summary;55
6.15;Suggested Reading;57
7;Environmental Allergens;58
7.1;2.1 Overview of Allergens;58
7.2;2.2 Pollens;59
7.3;2.3 Fungal Allergens;74
7.4;2.4 Indoor Allergens;80
7.5;2.5 Animal Allergens;84
7.6;2.6 Cockroach Allergen;89
7.7;2.7 Clinical Vignettes;91
7.8;Suggested Reading;94
8;Allergen Testing and Allergen Immunotherapy;95
8.1;3.1 Allergen Testing;95
8.2;3.2 Allergen Immunotherapy;107
8.3;3.3 Summary;125
8.4;3.4 Clinical Vignettes;125
8.5;Suggested Reading;131
9;Allergic Rhinitis and Rhinosinusitis;133
9.1;4.1 Overview;133
9.2;4.2 Nasal Anatomy and Function;134
9.3;4.3 Clinical Overview;137
9.4;4.4 Allergic Rhinitis;137
9.5;4.5 Nonallergic Rhinitis and Rhinosinusitis;151
9.6;4.6 Infectious-Acute Rhinosinusitis;151
9.7;4.7 Chronic Rhinosinusitis;156
9.8;4.8 Infectious Chronic Rhinosinusitis;157
9.9;4.9 Allergic Fungal Rhinosinusitis;160
9.10;4.10 Chronic Eosinophilic (Fungal or Hyperplastic) Rhinosinusitis;161
9.11;4.11 Systemic Disease;162
9.12;4.12 Noninfectious Structural Rhinosinusitis;162
9.13;4.13 Noninfectious Nonstructural Rhinitis and Rhinosinusitis;167
9.14;4.14 Clinical Vignettes;171
9.15;Suggested Reading;179
10;Allergic Eye Disease;181
10.1;5.1 Overview;181
10.2;5.2 Basic Eye Anatomy;181
10.3;5.3 Approach to the Patient;183
10.4;5.4 Allergic and Allergic-Like Eye Disease;185
10.5;5.5 Clinical Vignettes;200
10.6;Suggested Reading;203
11;Asthma;204
11.1;6.1 Overview;204
11.2;6.2 Epidemiology;205
11.3;6.3 Pathophysiology;205
11.4;6.4 Clinical Presentation and Differential Diagnosis;212
11.5;6.5 Classification of Asthma;232
11.6;6.6 Evaluation of Factors Contributing to Asthma Severity;239
11.7;6.7 Treatment;248
11.8;6.8 Clinical Vignettes;286
11.9;Suggested Reading;292
12;Urticaria and Angioedema;294
12.1;7.1 Description and Epidemiology;294
12.2;7.2 Pathophysiology;295
12.3;7.3 Acute Urticaria: Etiologies;296
12.4;7.4 Chronic Urticaria;297
12.5;7.5 Urticaria-Angioedema-Associated Disorders;306
12.6;7.6 Patient Evaluation;310
12.7;7.7 Medications Used in the Treatment of Acute and Chronic Urticaria;315
12.8;7.8 Therapy Recommendations;320
12.9;7.9 Clinical Vignettes;320
12.10;Suggested Reading;324
13;Atopic and Contact Dermatitis;326
13.1;8.1 Atopic Dermatitis;326
13.2;8.2 Contact Dermatitis;348
13.3;8.3 Clinical Vignettes;368
13.4;Suggested Reading;373
14;Drug Allergy;375
14.1;9.1 Epidemiology;375
14.2;9.2 Definitions;375
14.3;9.3 Pathophysiology and Clinical Manifestations;376
14.4;9.4 Clinical Evaluation of Suspected Drug Sensitivity;385
14.5;9.5 Therapy and Management;389
14.6;9.6 Special Medication Reactions;394
14.7;9.7 Clinical Vignettes;402
14.8;Suggested Reading;405
15;Food Allergy;406
15.1;10.1 Definitions;406
15.2;10.2 Epidemiology;406
15.3;10.3 Pathophysiology;407
15.4;10.4 Food Allergens;411
15.5;10.5 Approach to Patients;415
15.6;10.6 Clinical Disorders;417
15.7;10.7 Management;434
15.8;10.8 Food Additive Reactions;436
15.9;10.9 Summary;438
15.10;10.10 Clinical Vignettes;438
15.11;Suggested Reading;444
16;Anaphylaxis and Anaphylactoid Reactions;446
16.1;11.1 Definition and Epidemiology;446
16.2;11.2 Pathophysiology;447
16.3;11.3 History and Physical Examination;449
16.4;11.4 Risk Factors;450
16.5;11.5 Common Causes of Anaphylactic and Anaphylactoid Reactions;451
16.6;11.6 Idiopathic Anaphylaxis;461
16.7;11.7 Differential Diagnosis;462
16.8;11.8 Diagnosis and Diagnostic Testing;465
16.9;11.9 Management;468
16.10;11.10 Clinical Vignettes;472
16.11;Suggested Reading;475
17;Stinging Insect Allergy;477
17.1;12.1 Introduction;477
17.2;12.2 Identification of Stinging Insects;477
17.3;12.3 Reactions to Stinging Insects;480
17.4;12.4 Diagnostic Testing;482
17.5;12.5 Management;485
17.6;12.6 Conclusion;488
17.7;12.7 Clinical Vignettes;489
17.8;Suggested Reading;490
18;Index;492