Wendt Protein-Protein Interactions

1. Auflage 2012
ISBN: 978-3-642-28965-1
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 8, 276 Seiten

Reihe: Topics in Medicinal Chemistry

Michael D. Wendt
Protein-Protein Interactions as Drug TargetsShaomeng Wang , Yujun Zhao , Denzil Bernard , Angelo Aguilar , Sanjeev Kumar
Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics Kurt Deshayes , Jeremy Murray , Domagoj Vucic
The Development of Small-Molecule IAP Antagonists for the Treatment of Cancer John F. Kadow , David R. Langley , Nicholas A. Meanwell , Michael A. Walker , Kap-Sun Yeung , Richard Pracitto
Protein-Protein Interaction Targets to Inhibit HIV-1 Infection
Nicholas A. Meanwell , David R. Langley
Inhibitors of Protein-Protein Interactions in Paramyxovirus Fusion - a Focus on Respiratory Syncytial VirusAndrew B. Mahon , Stephen E. Miller , Stephen T. Joy , Paramjit S. Arora
Rational Design Strategies for Developing Synthetic Inhibitors of Helical Protein Interfaces Michael D. Wendt
The Discovery of Navitoclax, a Bcl-2 Family Inhibitor 

Autoren/Hrsg.

Wendt, Michael D.

Inhaltsverzeichnis

1;Protein-Protein Interactions;4
2;Topics in Medicinal Chemistry Also Available Electronically;8
3;Aims and Scope;8
4;Preface to the Series;10
5;Preface;12
6;Contents;16
7;Contributors;18
8;Protein-Protein Interactions as Drug Targets;20
9;Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics;75
10;The Development of Small-Molecule IAP Antagonists for the Treatment of Cancer;98
11;Protein-Protein Interaction Targets to Inhibit HIV-1 Infection;121
12;Inhibitors of Protein-Protein Interactions in Paramyxovirus Fusion: A Focus on Respiratory Syncytial Virus;182
13;Rational Design Strategies for Developing Synthetic Inhibitors of Helical Protein Interfaces;212
14;The Discovery of Navitoclax, a Bcl-2 Family Inhibitor;246
15;Index;274