E-Book, Englisch, 220 Seiten, eBook
Reihe: Cancer Drug Discovery and Development
ISBN: 978-3-030-05067-2
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: Wasserzeichen (»Systemvoraussetzungen)
Unique to the volume will be a specific focus on the UPR and its role in cancer biology, as well as a discussion of the role of the UPR in drug responses and resistance in cancer.
Zielgruppe
Research
Autoren/Hrsg.
Weitere Infos & Material
Introduction: The Unfolded Protein Response.- Endoplasmic Reticulum Stress Signaling During Development.- Regulation of the Unfolded Protein Response and its Roles in Tumorigenesis and Cancer Therapy.- ATF4, Hypoxia and Treatment Resistance in Cancer.- Role of Protein Translation in the Unfolded Protein Response.- Roles of Spliced and Unspliced XBP1 in Breast Cancer.- The Unfolded Protein Response in Triple-Negative Breast Cancer.- The Unfolded Protein Response as an Integrator of Response to Endocrine Therapy in Estrogen Receptor Positive Breast Cancer.- Outside the Endoplasmic Reticulum: Non-Canonical GRP78 Signaling.- Autophagy and the Unfolded Protein Response in Neurodegenerative Diseases.- Index.