1. Auflage 2019,
220 Seiten, Gebunden, Book, Format (B × H): 164 mm x 244 mm, Gewicht: 500 g
Reihe: Cancer Drug Discovery and Development
Verlag: Springer, Berlin
Clarke The Unfolded Protein Response in Cancer
Unique to the volume will be a specific focus on the UPR and its role in cancer biology, as well as a discussion of the role of the UPR in drug responses and resistance in cancer.
Weitere Infos & Material
Chapter 1: Introduction: The Unfolded Protein Response Chapter 2: Endoplasmic Reticulum Stress Signaling During Development Chapter 3: Regulation of the Unfolded Protein Response and its Roles in Tumorigenesis and Cancer Therapy Chapter 4: ATF4, Hypoxia and Treatment Resistance in Cancer Chapter 5: Role of Protein Translation in the Unfolded Protein Response Chapter 6: Roles of Spliced and Unspliced XBP1 in Breast Cancer Chapter 7: The Unfolded Protein Response in Triple-Negative Breast Cancer Chapter 8: The Unfolded Protein Response as an Integrator of Response to Endocrine Therapy in Estrogen Receptor Positive Breast Cancer Chapter 9: Outside the Endoplasmic Reticulum: Non-Canonical GRP78 Signaling Chapter 10: Autophagy and the Unfolded Protein Response in Neurodegenerative Diseases Index