Pyrazole-Based Drug Discovery

Erscheinungsjahr 2021
ISBN: 978-0-12-824140-0
Verlag: Elsevier Science

Buch, Englisch, 370 Seiten, Format (B × H): 152 mm x 229 mm

Pyrazole-Based Drug Discovery outlines complexities of the pyrazole scaffold used in drug discovery, including derivative chemistry, structural properties, methods of synthesis, and practical implementations. Designed as a guide for both experts and students working in this and related areas, this volume will facilitate the continued design and development of novel pharmaceuticals based on pyrazole and its derivatives. Pyrazole is a novel heterocycle with anti-fungal, antimicrobial, anti-tubercular, and antipsychotic pharmacological activities, proving to be a promising agent for medicinal chemists to synthesize various new chemical entities with desired biological activities.

Heterocyclic compounds are of central importance to medicinal chemistry, as demonstrated by the high percentage of marketable drugs that feature heterocyclic fragments in their structures. As starting points for drug discovery, they offer a broad range of attractive properties, and a detailed understanding of the particular characteristics of each is of great benefit to researchers. This book is ideal for researchers working in organic and medicinal chemistry both in academia and industry.

Autoren/Hrsg.

Dighe, Nachiket S

Laware, Ravindra B

Fachgebiete

• Naturwissenschaften Chemie Organische Chemie

Inhaltsverzeichnis

1. Journey of pyrazole: Phenazone to modern medicine2. Pyrazole in Medicinal Chemistry 3. Synthesis of Pyrazole and Fused Pyrazole4. Future scope in pyrazole synthesis

Über Autor(innen)

Laware, Ravindra B
Dr. Ravindra B Laware has 18 years of experience in academics and research. He has published more than 67 research and review articles in various national and international journals. He has guided 46 students for Postgraduate research work. He is a reviewer for many national and international journals. He has presented more than 50 research papers in various national and international conferences, seminars and workshops.

Dighe, Nachiket S
Dr Nachiket S Dighe has 18 years of experience in academics and research. He has published more than 140 research and review articles in various national and international journals. He has guided more than 65 PG students for their research work. He has published two books on organic chemistry. He is reviewer for many national and international journals. He has presented more than 50 research papers in various national and international conferences, seminars and workshops.