Dittmar / Liberles Evolution after Gene Duplication

1. Auflage 2011
ISBN: 978-0-470-61989-6
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 426 Seiten, E-Book

Gene duplication has long been believed to have played a major rolein the rise of biological novelty through evolution of new functionand gene expression patterns. The first book to examine geneduplication across all levels of biological organization,Evolution after Gene Duplication presents a comprehensivepicture of the mechanistic process by which gene duplication mayhave played a role in generating biodiversity.
Key Features:
* Explores comparative genomics, genome evolution studies andanalysis of multi-gene families such as Hox, globins,olfactory receptors and MHC (immune system)
* A complete post-genome treatment of the topic originallycovered by Ohno's 1970 classic, this volume extends coverageto include the fate of associated regulatory pathways
* Taps the significant increase in multi-gene family data thathas resulted from comparative genomics
* Comprehensive coverage that includes opposing theoreticalviewpoints, comparative genomics data, theoretical and empiricalevidence and the role of bioinformatics in the study of geneduplication
This up-to-date overview of theory and mathematical models alongwith practical examples is suitable for scientists across variouslevels of biology as well as instructors and graduate students.

Autoren/Hrsg.

Dittmar, Katharina

Liberles, David A.

Liberles, David

Inhaltsverzeichnis

Contributors.
Preface
1 Understanding Gene Duplication through Biochemistry andPopulation Genetics (David A. Leberles, Grigory Kolesov, andKatharina Dittmar).
2 Functional Divergence of Duplicated Genes (Takashi Makino,David G. Knowles, and Aoife McLysaght).
3 Duplication Retention After Small- and Large-ScaleDuplications (Steven Maere and Yves Van de Peer).
4 Gene Dosage and Duplication (Fyodor A. Kondrashov).
5 Myths and Realities of Gene Duplication (Austin L. Hughesand Robert Friedman).
6 Evolution After and Before Gene Duplication? (TobiasSikosek and Erich Bornberg-Bauer).
7 Protein Products of Tandem Gene Duplication: A Structural View(William R. Taylor and Michael I. Sadowski).
8 Statistical Methods for Detecting Functional Divergence ofGene Familiies (Xun Gu).
9 Mapping Gene Gains and Losses Among Metazoan Full GenomesUsing an Integrated Phylogenetic Framework (Athanasia C. Tzika,Raphaël Helaers, and Michel C. Milinkovitch).
10 Reconciling Phylogenetic Trees (Oliver Eulenstein,Snehalata Huzurbazar, and David A. Liberles).
11 On the Energy and Material Cost of Gene Duplication(Andreas Wagner).
12 The Fate of a Duplication in a Network Context (Orkun S.Soyer).
13 Evolutionary and Functional Aspects of Genetic Redundancy(Ran Kafri and Tzachi Pilpel).
14 A Phylogenomic Approach to the Evolutionary Dynamics of GeneDuplication in Birds (Gene L. Organ, Matthew D. Rasmussen, MaudeW. Baldwin, Manolis Kellis, and Scott V. Edwards).
15 Gene and Genome Duplications in Plants (Pamela S. Soltis,J. Gordon Burleigh, Andre S. Chanderbali, Mi-Jeong Yoo, and DouglasE. Soltis).
16 Whole Genome Duplications and the Radiation of Vertebrates(Shigehiro Kuraku and Axel Meyer).
Index.