Meynial-Denis Glutamine

Biochemistry, Physiology, and Clinical Applications
1. Auflage 2017
ISBN: 978-1-4822-3429-9
Verlag: CRC Press

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Beschreibung

Glutamine: Biochemistry, Physiology, and Clinical Applications describes the different functions of glutamine (Gln) in animals and humans. Gln is both a nutrient and a signaling molecule, and its functions go beyond those of a simple metabolic fuel or protein precursor. This book has gathered together, in an unbiased and critical manner, all the available evidence and research on Gln including pathology (neurological diseases, intestinal diseases, critical illness, and cancer), physiology (successful aging), catabolic states, immunity, and exercise. Special attention is given to the potential benefit of Gln in states of insulin resistance and the role of Gln as a "conditionally essential" amino acid.
The contributors are either pioneers or experts in the area of Gln from all around the globe, including Australia, Brazil, Canada, Europe, China, and the United States. This book is a valuable source of information for nutrition scientists, medical doctors, sports scientists, food scientists, dietitians, and anyone interested in nutrition. It is also a valuable resource for students in these fields and will be an important addition to university libraries.

Autoren

Autoren

Meynial-Denis, Dominique

Herausgeber

Meynial-Denis, Dominique

Über den Autor

Meynial-Denis, Dominique
Dominique Meynial-Denis, Ph.D., is a Researcher at Laboratoire d'Etude de Metabolisme Azote INRA, Centre de Recherches de Clermont-Ferrand-Theix, Lyon, France.

Inhaltsverzeichnis

INTRODUCTIONMorey W. Haymond

BASICS OF GLUTAMINE METABOLISM
An introduction to glutamine metabolism Vinicius Cruzat and Philip Newsholme

NEW DATA ON THE BIOCHEMISTRY OF GLUTAMINE
Intestinal glutamine synthetase co-localizes with goblet cells and decreases enterocyte proliferationYouji He, Theodorus BM Hakvoort, Jacqueline LM Vermeulen and Wouter H. Lamers

Glutaminase isoforms and glutamine metabolismCurthoys et al.

MOLECULAR AND CELLULAR ASPECTS OF GLUTAMINE METABOLISM
The importance of glutamine to insulin secretion, insulin action and glycaemic control Vinicius Cruzat, Gaewyn Ellison, Cyril Mamotte and Philip Newsholme
Glutamine and autophagy Rolf Gebhardt

Novel aspects on the regulation of glutamine and ammonia metabolism by morphogensRolf Gebhardt, Jan Böttger, Eugenia Marbach, Madlen Matz-Soja

GLUTAMINE, THE BRAIN AND NEUROLOGICAL DISEASES
The role of glutamine in brain pathology Albrecht et al.

Brain glutamine and hepatic encephalopathyRoger F. Butterworth and Chantal Bemeur

Change of glutamate/glutamine amounts in the striatum in a murin model of Parkinson's diseaseCarine Chassain1, Guy Bielicki2, Jean-Pierre Renou3, Franck Durif1,4

GLUTAMINE AND THE INTESTINAL TRACT
Glutamine and intestinal physiology and physiopathology François Blachier1, Xiangfeng Kong2, Guoyao Wu3, Daniel Tomé1, Antonio Lancha Jr4, Mireille Andriamihaja1, Yulong Yin2

Glutamine: General Facilitator of Gut Absorption and RepairRhoads et al.

Therapeutic role of glutamine in inflammatory bowel disease Hongyu Xue and Paul Wischmeyer

GLUTAMINE AND THE CATABOLIC STATE

PART I: ROLE OF GLUTAMINE IN CRITICAL ILLNESS
SECTION A: DURING CHILDHOOD

Glutamine in the Critically Ill Neonate Neu et al

SECTION B: FROM ADULTHOOD

Rationale for and efficacy of glutamine supplementation in critical illness Farook Jahoor, Christina Kao

The Role of Glutamine and Oxidative Injury Pathways in Critically Ill Patients Naji Abumrad, Kaushik Mukherjee and Addison May

Glutamine supplementation in critical illness: clinical endpoints Marie Smedberg and Jan Wernerman

Glutamine supplementation in critical illness: action mechanismsMoïse Coëffier and Pierre Déchelotte

The clinical role of glutamine supplementation in disease Giacomo Garibotto, Alice Bonanni, Giacomo Deferrari, Daniela Verzola

PART II: ROLE OF GLUTAMINE IN CANCER
Glutamine transport and metabolism in cancerPaige J. Bothwell, Clare C. Kron and Barrie P. Bode

Glutamine as a new therapeutic target in cancer: use of hyperpolarized magnetic resonance spectroscopyDominique Meynial-Denis1 and Jean-Pierre Renou2

GLUTAMINE, IMMUNITY AND EXERCISE
Glutamine and the immune system: an overview Philip Calder

Glutamine and exercise and immune systemMarcelo Macedo Rogero

The Role of Glutamine in Exercise-induced Immunodepression in HumansLindy Castell and Natalie Redgrave

GLUTAMINE AND AGING
Glutamine metabolism in old ageDominique Meynial-Denis

Zielgruppe

This book is intended for health practitioners, clinicians, nurses, nutritionists/dietitians and biochemists. It also would be useful to nutrition scientists, senior undergraduate/graduate nutrition students (biochemistry or nutrition courses) and molecular biologists.

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