Lentiviral Vectors

Softcover Nachdruck of the original 1. Auflage 2002
ISBN: 978-3-642-62667-8
Verlag: Springer

Buch, Englisch, Band 261, 260 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 417 g

Reihe: Current Topics in Microbiology and Immunology

For the first time a compilation of chapters that depict the biological bases underlying the development of lentiviral vectors, the techniques involved in the manufacture of this new gene delivery tool, and its most promising applications.

Zielgruppe

Research

Autoren/Hrsg.

Trono, Didier

Fachgebiete

• Naturwissenschaften Biowissenschaften Mikrobiologie
• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik

Inhaltsverzeichnis

List of Contents.- Molecular Biology of Lentivirus-Mediated Gene Transfer.- HIV-1-Derived Lentiviral Vectors.- Lentiviral Vectors Derived from Simian Immunodeficiency Virus.- Nonprimate Lentiviral Vectors.- Production of Lentiviral Vectors.- Biosafety Issues in Lentivector Production.- Lentiviral Vector Targeting.- Integration Site Selection by Lentiviruses: Biology and Possible Control.- Improving the Post-Transcriptional Aspects of Lentiviral Vectors.- Lentiviruses as Vectors for CNS Diseases.- Lentiviral Vectors for the Gene Therapy of Lympho-Hematological Disorders.- Lentiviral Vectors for Gene Therapy of HIV-Induced Disease.- Opportunities for the Use of Lentiviral Vectors in Human Gene Therapy.