Ipscs from Diverse Species

Erscheinungsjahr 2020
ISBN: 978-0-12-822228-7
Verlag: Elsevier Science

Buch, Englisch, 272 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 660 g

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.

iPSCs from Diverse Species, Volume 2 addresses how induced pluripotent stem cells (iPSCs) can be derived from different species.

The volume teaches the reader about modern state-of-the-art methodologies to derive iPSCs from distinct species. This volume will cover how to derive iPSCs from species like nonhuman primates, horses, dogs, pigs, rats, rabbits, and others. It also discusses the importance of iPSCs in species conservation. Detailed description on methods used to obtain iPSCs from humans and other species expands the knowledge and understanding of stem cell biology and provides a potent tool to model diseases.

The volume is written for researchers and scientists in stem cell biology, and regenerative medicine and is contributed by world-renowned authors in the field.

Autoren/Hrsg.

Birbrair, Alexander

Fachgebiete

• Naturwissenschaften Biowissenschaften Zellbiologie

Inhaltsverzeichnis

1. Human iPSCs and Their Uses in Developmental Toxicology 2. Induced Pluripotent Stem Cells from Non-Human Primates 3. Equine Induced Pluripotent Stem Cells 4. Canine Induced Pluripotent Stem Cells: An In Vitro Approach to Validate the Dog as a Large Animal Model for Alzheimer's Disease 5. Porcine iPSCs 6. Bovine iPSC and applications in precise genome engineering 7. Induced Pluripotent Stem Cells from Buffalo 8. Establishment of Induced Pluripotent Stem Cell from Prairie Vole Derived Fibroblast 9. Rabbit Induced Pluripotent Stem Cells: The Challenges 10. Naked Mole Rat iPSCs and Their Non-Canonical Features: A Novel Tool for Aging Research 11. Induced Pluripotent Stem Cells in Species Conservation: Advantages, Applications and the Road Ahead

Über Autor(innen)

Birbrair, Alexander
Dr. Alexander Birbrair received his bachelor's biomedical degree from Santa Cruz State University in Brazil. He completed his PhD in Neuroscience, in the field of stem cell biology, at the Wake Forest School of Medicine under the mentorship of Osvaldo Delbono. Then, he joined as a postdoc in stem cell biology at Paul Frenette's laboratory at Albert Einstein School of Medicine in New York. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA), and in 2021, he was elected affiliate member of The World Academy of Sciences (TWAS). He is the Founding Editor and Editor-in-Chief of Current Tissue Microenvironment Reports, and Associate Editor of Molecular Biotechnology. Alexander also serves in the editorial board of several other international journals: Stem Cell Reviews and Reports, Stem Cell Research, Stem Cells and Development, and Histology and Histopathology.