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E-Book

E-Book, Englisch, 300 Seiten, E-Book

Reihe: Novartis Foundation Symposia

Bock / Goode Tinkering

The Microevolution of Development
1. Auflage 2008
ISBN: 978-0-470-31940-6
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

The Microevolution of Development

E-Book, Englisch, 300 Seiten, E-Book

Reihe: Novartis Foundation Symposia

ISBN: 978-0-470-31940-6
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)



Much recent research in evolutionary developmental biology hasfocused on the origin of new body plans. However, most evolutionarychange at the population and species level consists of tinkering:small-scale alterations in developmental pathways within a singlebody plan. Such microevolutionary events have been well studied ona population genetic level and from the perspective of adaptivephenotypic evolution, but their developmental mechanisms remainpoorly studied.
This book explores both theoretical and practical issues oftinkering. It features a wide range of perspectives to addressseveral fundamental questions. How does tinkering occurdevelopmentally, and how is it manifested phenotypically? Are thedevelopmental mechanisms by which tinkering occur different fromthose that underlie larger evolutionary changes? What are thedevelopmental constraints on tinkering? And how do we testhypotheses about microevolutionary shifts in development from thefossil record?
With contributions from experts in a range of fields, thisfascinating book makes exciting reading for anyone studyingevolution, developmental biology or genetics.

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Weitere Infos & Material


Symposium on Tinkering: the microevolution of development, held atthe Novartis Foundation, London, 11-13 July 2006.
Editors: Gregory Bock (Organizer) and Jamie Goode.
This symposium is based on a proposal made by Brian Hall.
Daniel E. Lieberman The evolutionary developmental biology oftinkering: an introduction to the challenge.
Manfred D. Laubichler Tinkering: a conceptual and historicalevaluation
Discussion.
Rudolf A. Raff and Elizabeth C. Raff Tinkering: new embryos fromold-rapidly and cheaply.
Discussion.
James M. Cheverud The relationship between development andevolution through heritable variation.
Discussion.
Adam S. Wilkins Genetic networks as transmitting and amplifyingdevices for natural genetic tinkering.
Discussion.
Paul M. Brakefield Butterfly eyespot patterns and howevolutionary tinkering yields diversity.
Discussion.
General discussion I.
Günter P. Wagner and Anna Marie Pyle Tinkering withtranscription factor proteins: the role of transcription factoradaptation in developmental evolution.
Discussion.
Denis Duboule, Basile Tarchini, Jozsef Zàkàny andMarie Kmita Tinkering with constraints in the evolution of thevertebrate limb anterior-posterior polarity.
Discussion.
Irma Thesleff, Elina Järvinen and Marika SuomalainenAffecting tooth morphology and renewal by fine-tuning the signalsmediating cell and tissue interactions.
Discussion.
General discussion II.
Benedikt Hallgrimsson, Daniel E. Lieberman, Nathan M. Young,Trish Parsons and Steven Wat Evolution of covariance in themammalian skull.
Discussion.
David L. Stern The developmental genetics ofmicroevolution.
Discussion.
Jukka Jernvall and Isaac Salazar-Ciudad The economy of tinkeringmammalian teeth.
Discussion.
Michael A. Bell, Kaitlyn E. Ellis and Howard I. Sirotkin Pelvicskeleton reduction and Pitx1 expression in threespine sticklebackpopulations.
Discussion.
Michael I. Coates, Marcello Ruta and Peter J. Wagner Usingpatterns of fin and limb phylogeny to testdevelopmental-evolutionary scenarios.
Discussion.
Rebecca R. Ackermann Craniofacial variation and developmentaldivergence in primate and human evolution.
Discussion.
Contributor Index.
Subject Index.


The Novartis Foundation is an international scientific andeducational charity which promotes the study and general knowledgeof science and in particular encourages international co-operationin scientific research.
Chair: DANIEL LIEBERMAN, Harvard University, Cambridge,USA



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