Brennan / Kirschner Bio-inspired Materials for Biomedical Engineering

1. Auflage 2014
ISBN: 978-1-118-84343-7
Verlag: John Wiley & Sons
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 400 Seiten, E-Book

Reihe: Wiley-Society for Biomaterials

This book covers the latest bio-inspired materials synthesistechniques and biomedical applications that are advancing the fieldof tissue engineering. Bio-inspired concepts for biomedicalengineering are at the forefront of tissue engineering andregenerative medicine. Scientists, engineers and physicians areworking together to replicate the sophisticated hierarchicalorganization and adaptability found in nature and selected byevolution to recapitulate the cellular microenvironment. Thisbook demonstrates the dramatic clinical breakthroughs that havebeen made in engineering all four of the major tissue types andmodulating the immune system.
Part I (Engineering Bio-inspired Material Microenvironments)covers Bio-inspired Presentation of Chemical Cues, Bio-inspiredPresentation of Physical Cues, and Bio-inspired Integration ofNatural Materials.
Part II (Bio-inspired Tissue Engineering) addresses tissueengineering in epithelial tissue, muscle tissue, connective tissue,and the immune system.

Autoren/Hrsg.

Brennan, Anthony B.

Kirschner, Chelsea M.

Inhaltsverzeichnis

Contributors vii
Preface xi
INTRODUCTION 1
Sang Jin Lee and Anthony Atala
PART I ENGINEERING BIO-INSPIRED MATERIAL MICROENVIRONMENTS5
CHAPTER 1 ECM-INSPIRED CHEMICAL CUES: BIOMIMETIC MOLECULES ANDTECHNIQUES OF IMMOBILIZATION 7
Roger Y. Tam, Shawn C. Owen, and Molly S. Shoichet
CHAPTER 2 DYNAMIC MATERIALS MIMIC DEVELOPMENTAL AND DISEASECHANGES IN TISSUES 25
Matthew G. Ondeck and Adam J. Engler
CHAPTER 3 THE ROLE OF MECHANICAL CUES IN REGULATING CELLULARACTIVITIES AND GUIDING TISSUE DEVELOPMENT 45
Liming Bian
CHAPTER 4 CONTRIBUTION OF PHYSICAL FORCES ON THE DESIGN OFBIOMIMETIC TISSUE SUBSTITUTES 59
Menekse Ermis, Erkan Türker Baran, Tu?ba Dursun, EzgiAntmen, and Vasif Hasirci
CHAPTER 5 CELLULAR RESPONSES TO BIO-INSPIRED ENGINEEREDTOPOGRAPHY 77
Chelsea M. Kirschner, James F. Schumacher, and Anthony B.Brennan
CHAPTER 6 ENGINEERING THE MECHANICAL AND GROWTH FACTOR SIGNALINGROLES OF FIBRONECTIN FIBRILS 99
Christopher A. Lemmon
CHAPTER 7 BIOLOGIC SCAFFOLDS COMPOSED OF EXTRACELLULAR MATRIX ASA NATURAL MATERIAL FOR WOUND HEALING 111
Elizabeth W. Kollar, Christopher L. Dearth, and Stephen F.Badylak
CHAPTER 8 BIO-INSPIRED INTEGRATION OF NATURAL MATERIALS125
Albino Martins, Marta Alves da Silva, Ana Costa-Pinto, Rui L.Reis, and Nuno M. Neves
PART II BIO-INSPIRED TISSUE ENGINEERING 151
CHAPTER 9 BIO-INSPIRED DESIGN OF SKIN REPLACEMENT THERAPIES153
Dennis P. Orgill
CHAPTER 10 EPITHELIAL ENGINEERING: FROM SHEETS TO BRANCHED TUBES161
Hye Young Kim and Celeste M. Nelson
CHAPTER 11 A BIOMIMETIC APPROACH TOWARD THE FABRICATION OFEPITHELIAL-LIKE TISSUE 175
Hongjun Wang and Meng Xu
CHAPTER 12 NANO- AND MICROSTRUCTURED ECM AND BIOMIMETICSCAFFOLDS FOR CARDIAC TISSUE ENGINEERING 195
Quentin Jallerat, John M. Szymanski, and Adam W.Feinberg
CHAPTER 13 STRATEGIES AND CHALLENGES FOR BIO-INSPIREDCARDIOVASCULAR BIOMATERIALS 227
Elaine L. Lee and Joyce Y. Wong
CHAPTER 14 EVALUATION OF BIO-INSPIRED MATERIALS FOR MINERALIZEDTISSUE REGENERATION USING TYPE I COLLAGEN REPORTER CELLS 259
Liisa T. Kuhn, Emily Jacobs, and A. Jon Goldberg
CHAPTER 15 LEARNING FROM TISSUE EQUIVALENTS: BIOMECHANICS ANDMECHANOBIOLOGY 281
David D. Simon and Jay D. Humphrey
CHAPTER 16 MIMICKING THE HEMATOPOIETIC STEM CELL NICHE BYBIOMATERIALS 309
Eike Müller, Michael Ansorge, Carsten Werner, and TiloPompe
CHAPTER 17 ENGINEERING IMMUNE RESPONSES TO ALLOGRAFTS 327
Anthony W. Frei and Cherie L. Stabler
CHAPTER 18 IMMUNOMIMETIC MATERIALS 357
Jamal S. Lewis and Benjamin G. Keselowsky
Index 371

Über Autor(innen)

Anthony B. Brennan is the Margaret A. Ross EndowedProfessor of Materials Science and Engineering and a professor ofBiomedical Engineering at the University of Florida. Hereceived his Bachelor's degree in chemistry from State Universityof New York at Potsdam in 1975 and his Ph.D. in MaterialsEngineering Science from Virginia Polytechnic Institute and StatueUniversity in 1990. Dr. Brennan has been a member of thefaculty at the University of Florida since 1991. Hismaterials focus is on the structure of the interphase between thecell and the substrate.Chelsea M. Kirschner obtained a Bachelor's degree inMaterials Science and Engineering at the University of Florida in2006, and her Ph.D. in Biomedical Engineering from the Universityof Florida in 2010. Dr. Kirschner completed a postdoctoralresearch fellowship at the University of Colorado at Boulder in2013. Her research focused on the influence of spatially andtemporally patterned hydrogel architectures and chemistries onadult stem cell shape and differentiation. She is currently aBiomedical R&D Engineer at Sharklet Technologies in Aurora, CO.