Clinical and Molecular Aspects of Motor Neuron Disease

Erscheinungsjahr 2013
ISBN: 978-1-61504-428-3
Verlag: Biota Publishing

Buch, Englisch, 60 Seiten, Paperback, Format (B × H): 191 mm x 235 mm, Gewicht: 136 g

Reihe: Colloquium Series on Genomic and Molecular Medicine

In this e-book, motor neuron disease (MND) shall refer to amyotrophic lateral sclerosis (ALS), the most common neurodegenerative disorder affecting both the upper and lower motor neurons. With the discovery of C9ORF72 expansions in approximately 10% of all MND cases, in certain populations, we stand at the brink of a new era of MND research and hopefully treatment facilitated by the ability to associate a relatively large group of patients with a similar disease mechanism. This review will summarise both current clinical management of MND and our present understanding of the molecular pathogenesis of MND. Study of C9ORF72-MND has the potential to rapidly advance both of these aspects in the coming years.

Autoren/Hrsg.

Cooper-Knock, Johnathan

Jenkins, Thomas

Shaw, Pamela J.

Inhaltsverzeichnis

- Clinical Aspects of MND
- Molecular Aspects of MND
- References
- Author Biographies