Buch, Englisch, 288 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 7172 g
Dietary Factors and Pharmacology
Buch, Englisch, 288 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 7172 g
Reihe: Methods in Pharmacology and Toxicology
ISBN: 978-1-4614-9226-9
Verlag: Springer
Focused on the discovery of precise molecular targets for the development of the cancer preventive agents, Cancer Prevention: Dietary Factors and Pharmacology provides researchers and non-researchers with practical methodologies for developing and validating small molecule and phytochemical-derived drug discovery and mechanisms by which these compounds can modulate distinct target proteins involved in oncogenic signaling. While this volume is primarily focused toward cancer prevention research, the range of techniques demonstrated in the book also provides an introduction of cancer prevention research methods to researchers outside the field. Chapters deal with a critical discussion of both laboratory and clinical topics, with each chapter containing both a discursive section along with a detailed methods section. As part of the Methods in Pharmacology and Toxicology series, this meticulous volume includes the kind of key implementation advice that seeks to ensure successful results in the lab.
Practical and authoritative, Cancer Prevention: Dietary Factors and Pharmacology aims to guide research toward identifying molecular targets and conducting human studies with phytochemicals which would, ideally, provide an enhanced approach to the goal of personalized cancer prevention.
Zielgruppe
Professional/practitioner
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Präventivmedizin, Gesundheitsförderung, Medizinisches Screening
Weitere Infos & Material
1. Combining Computational and Experimental Methods for Identifying Molecular Targets of Phytochemicals
Ann M. Bode and Zigang Dong
2. Common Methods Used for the Discovery of Natural Anticancer Compounds
Min Tang, Xinfang Yu, Yiqun Jiang, Ying Shi, Xiaolan Liu, Wei Li, and Ya Cao
3. Nrf2-Target Approaches in Cancer Chemoprevention Mediated by Dietary Phytochemicals
Francisco Fuentes, Limin Shu, Jong Hun Lee, Zheng-Yuan Su, Kyeong-Ryoon Lee, and Ah-Ng Tony Kong
4. Methods to Analyze Chemopreventive Effect of Silibinin on Prostate Cancer Biomarkers Protein Expression
Gagan Deep, Swetha Inturi, and Rajesh Agarwal
5. An Approach to the Evaluation of Berries for Cancer Prevention with Emphasis on Esophageal Cancer
Gary D. Stoner, Li-Shu Wang, Laura A. Kresty, Dan Peiffer, Chieh-Ti Kuo, Yi-Wen Huang, Dian Wang, Ben Ransom, Steven Carmella, and Stephen S. Hecht
6. The Use of Mouse Models for Lung Cancer Chemoprevention Studies
Yian Wang, Michael S. You, Lucina C. Rouggly, and Ming You
7. The Azoxymethane Plus Dextran Sulfate Sodium-Induced Mouse Colon Cancer Model for the Study of Dietary Chemoprevention of Inflammation-Associated Carcinogenesis
Ha-Na Lee, Hye-Won Yum, and Young-Joon Surh
8. The Use of Seahorse Extracellular Flux Analyzer in Mechanistic Studies of Naturally-Occurring Cancer Chemopreventive Agents
Michelle B. Moura, Eun-Ryeong Hahm, Bennett Van Houten, and Shivendra V. Singh
9. Utilizing RNA-Seq to Define Phytochemical-Induced Alterations in Insulin and IGF Regulated Transcriptomes
Heather Beckwith and Douglas Yee
10. The Ex Vivo Use of Keratinocytes from Adult Mice to Define Stem Cell Activities in Cancer Research
Rebecca J. Morris, Nyssa Readio, Kelly M. Johnson, Anupama Singh, Heuijoon Park, Ashok Singh, and Todd F. Schuster
11. Quantitation of Acetaldehyde-DNA Adducts: Biomarkers of Alcohol Consumption
Silvia Balbo and Stephen S. Hecht
12. Imaging Tools in Discovery and Development of Phytochemical Chemopreventive Agents
Marna Ericson
13. Designing the Chemoprevention Trials of Tomorrow: Applying Lessons Learned from Past Definitive Trials
Karen Colbert Maresso and Ernest Hawk
