Inflammation and Natural Products

Erscheinungsjahr 2021
ISBN: 978-0-12-819218-4
Verlag: ACADEMIC PR INC

Buch, Englisch, 462 Seiten, Format (B × H): 191 mm x 234 mm, Gewicht: 930 g

Inflammation and Natural Products brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products, addressing specific chronic inflammatory diseases like cancer and the mechanistic aspects of the mode of action of some key natural products. Inflammation is a complicated process, driven by infection or injury or genetic changes, which results in triggering signalling cascades, activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and release of various oxidants and pro-inflammatory molecules in inflammatory cells. Excessive oxidants and inflammatory mediators have a harmful effect on normal tissue, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs and finally leading to systemic disorders. The emerging development of natural product formulations utilizing the unique anti-inflammatory compounds such as polyphenols, polysaccharides, terpenes, fatty acids, proteins and several other bioactive components has shown notable successes. Inflammation and Natural Products: Recent Development and Current Status provides a comprehensive resource, ranging from detailed explanation on inflammation to molecular docking strategies for naturally occurring compounds with anti-inflammatory activity. It is useful for graduate students, academic and professionals in the fields of pharmaceutical and medical sciences and specialists from natural product-related industries.

Zielgruppe

<p>Graduate students, academic and professionals in the fields of pharmaceutical and medical sciences and specialists from natural product-related industry</p>

Autoren/Hrsg.

Gopi, Sreeraj

Amalraj, Augustine

Kunnumakkara, Ajaikumar B.

Thomas, Sabu

Fachgebiete

• Naturwissenschaften Chemie Organische Chemie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Kardiologie, Angiologie, Phlebologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Gastroentereologie, Proktologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Komplementäre Medizin, Asiatische Medizin (TCM), Heilpraktiker
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

1. Inflammation - Symptoms, Reactions and Biochemistry
2. Molecular and genetic inflammation networks in major human diseases
3. Natural products in inflammation: The emerging trends and prospective goals
4. Natural products as modulator of signaling in inflammation
5. Natural products with anti-inflammatory activities against autoimmune myocarditis
6. Multi-target approach for natural products in inflammation
7. Anti-inflammatory activity of natural dietary flavonoids
8. Anti-inflammatory effects of turmeric and ginger
9. Potential anti-inflammatory natural products from marine algae
10. Natural product derived drugs for the treatment of inflammatory bowel diseases
11. Smart drug delivery systems of natural products for inflammation: from fundamentals to the clinic
12. Systems pharmacology and molecular docking strategies prioritize natural molecules as anti-inflammatory agents
13. Formulations, supplements and diets for anti-inflammation
14. Values of natural products to future anti-inflammatory pharmaceutical discovery
15. Metabolomic study of natural products in toxicity evaluation and toxicology biomarker identification

Über Autor(innen)

Kunnumakkara, Ajaikumar B.
Prof. Ajaikumar Kunnumakkara, is a faculty member in the Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam, India. He is also an Honorary Chair Professor in Nanoscience and Nanotechnology. He is the principal investigator of Unit of Excellence in cancer drug discovery (DBT, Govt. of India) and the coordinator of DBT (India) - AIST (Japan) International Laboratory for Advanced Biomedicine. He earned his doctorate in 2006 from Amala Cancer Research Center, Thrissur, affiliated with University of Calicut, Kerala, India. Dr. Kunnumakkara did postdoctoral work at the University of Texas MD Anderson Cancer Center, Houston, Texas, USA (2005-2008) and the National Cancer Institute of National Institutes of Health (2008-2010) where he was subsequently employed as an NIH Scientist until 2012. Dr. Kunnumakkara has also edited four monographs. He is an elected Fellow of Royal Society of Medicine, UK as well as belonging to many other esteemed institutions.

Gopi, Sreeraj
Dr. Sreeraj Gopi is the Co-Founder and Director of Molecules Food solutions Pvt Ltd, Zingon Naturals Pvt Ltd. He was the Chief Scientist at Plant Lipids Pvt Ltd. and Chief Scientific Officer at Aurea Biolabs Pvt Ltd., He has also served as an adjunct professor at universities including Stockholm University, Sweden, Siberian Federal University, Russia, and Mahatma Gandhi University, India. He completed his doctorate in organic chemistry and nanotechnology, and nano drug delivery working in the area of natural products, isolation, and biological activities. He published more than 175 international articles and filed more than 75 patents, in the US and Europe. At Plant Lipids, he developed many innovative products and technologies, and is responsible for driving the research team to excellence, as well as, implementing new projects, presenting scientific seminars to various customers. He was listed world's top 2% scientist list by Standford University.

Amalraj, Augustine
Dr. Augustine Amalraj is currently working as a Senior Scientist in the Department of Research and Development at Molecules Food Solutions Private Limited, Koratty, Thrissur, Kerala, India. He was worked as a Deputy Manager in the Department of Research and Development at Plant Lipids Private Limited and Aurea Biolabs Private Limited, Cochin, India. He obtained his Doctoral degree in Chemistry from Gandhigram Rural Institute - Deemed University, Gandhigram, Tamil Nadu, India. His research interests are in applied chemistry, food chemistry, natural product chemistry, environmental chemistry, chemosensors, and polymer and nanocomposite materials. He has published more than 60 research articles in international journals, as well as 22 book chapters, co-edited 10 books and filed 3 patents. He was listed among the top 2% of scientists in the world by Stanford University.

Thomas, Sabu
Dr. Thomas is the Vice-Chancellor and a Professor of Polymer Science and Engineering at Mahatma Gandhi University, India. Additionally, he serves as the Director of the School of Energy Materials at the same institution. Dr. Thomas is internationally recognized for his contributions to polymer science and engineering, covering polymer nanocomposites, elastomers, polymer blends, interpenetrating polymer networks, polymer membranes, green composites, nanocomposites, nanomedicine, and green nanotechnology. His groundbreaking inventions in polymer nanocomposites, polymer blends, green bionanotechnological, and nano-biomedical sciences have significantly contributed to the development of new materials in the automotive, space, housing, and biomedical fields. Dr. Thomas has been conferred with Honoris Causa (DSc) by the University of South Brittany, Lorient, France.