Capillary Electrophoresis-Mass Spectrometry for Proteomics and Metabolomics

Principles and Applications
1. Auflage 2022
ISBN: 978-3-527-34921-0
Verlag: WILEY-VCH

Buch, Englisch, 400 Seiten, Format (B × H): 170 mm x 244 mm, Gewicht: 682 g

The complete guide to CE-MS for metabolomics and proteomics analysis in clinical and biological research includes recent advances in sensitivity and reproducibility and numerous practical examples.

Autoren/Hrsg.

Ramautar, Rawi

Chen, David D. Y.

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
• Naturwissenschaften Chemie Analytische Chemie Massenspektrometrie, Spektroskopie, Spektrochemie

Inhaltsverzeichnis

1. Capillary Electrophoresis-Mass Spectrometry Interfacing: Principles and Recent Developments
2. Data Analysis Strategies in CE-MS for Metabolomics

3. Data Processing Workflow for Relative Quantification from Label-Free and Isobaric Labeling-Based Untargeted Shotgun Proteomics: From Database Search to Differential Expression Analysis
4. Data Processing in Metabolomics Capillary Electrophoresis-Mass Spectrometry
5. Utility and Advances of Capillary Electrophoresis-Mass Spectrometry for Metabolomics
6. Comprehensive Lipid Profiling by Multisegment Injection-Nonaqueous Capillary Electrophoresis-Mass Spectrometry: Expanding Coverage Beyond Hydrophilic Metabolites
7. Strategies for Identification of Modified Amino Acids with CE-MS in Metabolomics
8. CE-MS Approaches for Single-Cell Metabolomics
9. CE-MS Approaches for Peptidomics

10. Capillary Zone Electrophoresis-Mass Spectrometry for Top-Down Proteomics: Technological Development and Biological Applications

11. CE-MS Methods for the Characterization of Monoclonal Antibodies
12. CE and CE-MS Approaches for Glycan Analysis

13. CE-MS Approaches for Glyco(proteo)mic Analysis

Über Autor(innen)

Rawi Ramautar obtained his PhD on the development of capillary electrophoresis-mass spectrometry methods for metabolomics from Utrecht University (Netherlands) in 2010. Currently, he is a principal investigator at Leiden University where his group is involved in developing microscale analytical workflows for sample-restricted biomedical problems. Rawi Ramautar was recently selected for the Top 40 under 40 Power List of Analytical Scientists. He also serves as the editor of Microchemical Journal.
David Da Yong Chen obtained his Ph.D. in Chemistry in 1993 from the University of Alberta (Canada), where he also received postdoctoral training in Chemistry and Medical Microbiology. In July 1994, he joined the faculty at the University of British Columbia, where he is currently a Full Professor of Chemistry as well as an Associate Member in the Faculty of Medicine. Dr. Chen received the 2002 Royal Society of Chemistry (RSC, UK) Award in Analytical Separation Methods, and the 2003 Charles McDowell Award for Excellence in Research, a gold medal given to the most outstanding young scientist at UBC. For his contribution in analytical chemistry, Dr. Chen received the W. A. E. McBryde Medal and the Maxxam Award from the Canadian Society for Chemistry.