Vancik / Vancik Aromatic C-nitroso Compounds

2013
ISBN: 978-94-007-6337-1
Verlag: Springer Netherland
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 156 Seiten, eBook

Reihe: Biomedical and Life Sciences (R0)

This book is designed to collect and review the research covering main directions in investigations of aromatic nitroso compounds in last decades, and to present both, the academic aspects of this chemistry, as well as the open field of its applicability. The book is divided in five chapters. The basic structural properties of the nitroso aromatic molecules are described in the first chapter. The second chapter is an overview of the methods of preparations of aromatic nitroso and polynitroso compounds, including classical synthetic methods and some new preparative approaches. The third part deals with the physico-chemical properties of nitroso aromates and azodioxides, its structure, crystallography, quantum chemical calculations, spectroscopy, typical reactions, and especially it is focused on the dimerizations in the solid-state. In the fourth chapter is represented organometallic chemistry of nitroso aromatic molecules and its applications in catalysis. The last part of the book deals with the behavior of this class of compounds in the biological systems, reactions with biomolecules and the use in toxicology.

Zielgruppe

Research

Autoren/Hrsg.

Vancik, Hrvoj

Inhaltsverzeichnis

Introduction: Aliphatic and aromatic nitroso compounds1. Molecular structures1.1 Calculated molecular structures1.2 Experimental geometries2. An overview of synthetic methods for preparation of nitrosoaromatic compounds2.1 Reductive methods2.2 Oxidative methods2.3 Solid-state syntheses2.4 Enzyme catalyzed oxidations2.5 Direct nitrosation2.6 Heteroaromatic compounds2.7 Nitrosoaromatic compounds with more nitroso groups2.8 Synthesis of azoxides and azodioxides3. Molecular properties and spectroscopy3. 1 Physical Organic Chemistry3.1.1 Nature of the NO group. 3.1.2 Nucleophilic properties3.1.3 Reactions with nucleophiles3.1.3.1 Oxygen as nucleophile3.1.3.2 Sulfur as nucleophile3.1.3.3 Carbon as nucleophile3.1.3.4 Nitrogen as nucleophile3.1.4 Superacid medium3.1.5 Nitroso cycloadditions3.1.5.1 Stepwise cycloadditions3.2 Dimerizations and Spectroscopy3.2.1 NMR spectroscopy3.2.1.1 1HNMR3.2.1.2 Multinuclear NMR3.2.1.3 13C NMR3.2.1.4 14N NQR3.2.1.5 15N NMR spectra3.2.1.6 17O NMR3.2.2 UV-VIS spectroscopy3.2.3 Photoelectron spectroscopy3.3 Monomer-dimer equilibrium 3.3.1 Dimerizations and polymerizations of dinitroso compounds3.3.2 Vibrational spectroscopy3.3.3 Kinetics of dimerisation in solid-state3.3.4 Cross dimerizations3.3.5 Dimerizations of heteroaromatic derivatives3.3.6 Calculations of the reaction path3.4 Electrochemistry3.4.1 Aromatic nitroso compounds as spin traps3.5 Photochemistry3.5.1 Photoreactions including nitrosoaromatic intermediates4. Organometallic compounds4.1 Structures and properties of nitrosoaromatic-metal complexes4.2 Nitrosoaromatic-heme complexes5. Bilological systems5.1 Reactions with fatty acids and steroides5.2 Reactions with thiol consisting biomolecules5.3 Redox reactions and nitrosoaryl compounds in biological systemsReferencesSUBJECT INDEX