Buch, Englisch, 742 Seiten, Format (B × H): 225 mm x 285 mm, Gewicht: 2329 g
Reihe: ASM
Principles and Practices
Buch, Englisch, 742 Seiten, Format (B × H): 225 mm x 285 mm, Gewicht: 2329 g
Reihe: ASM
ISBN: 978-1-55581-620-9
Verlag: Wiley
Led by editors Karen Byers and Dawn Wooley, a team of expert contributors have outlined the technical nuts and bolts of biosafety and biosecurity within these pages. This book presents the guiding principles of laboratory safety, including: the identification, assessment, and control of the broad variety of risks encountered in the lab; the production facility; and, the classroom.
Specifically, Biological Safety covers
* protection and control elements--from biosafety level cabinets and personal protection systems to strategies and decontamination methods
* administrative concerns in biorisk management, including regulations, guidelines, and compliance
* various aspects of risk assessment covering bacterial pathogens, viral agents, mycotic agents, protozoa and helminths, gene transfer vectors, zooonotic agents, allergens, toxins, and molecular agents as well as decontamination, aerobiology, occupational medicine, and training
A resource for biosafety professionals, instructors, and those who work with pathogenic agents in any capacity, Biological safety is also a critical reference for laboratory managers, and those responsible for managing biohazards in a range of settings, including basic and agricultural research, clinical laboratories, the vivarium, field study, insectories, and greenhouses.
Zielgruppe
Researchers interested in laboratory safety, biodefense, and hazardous pathogens; Environmental health professionals; industrial researchers; technicians; students
Autoren/Hrsg.
Fachgebiete
- Naturwissenschaften Biowissenschaften Mikrobiologie
- Wirtschaftswissenschaften Betriebswirtschaft Bereichsspezifisches Management Arbeitsplatz, Arbeitsschutz, Gefahrstoffschutz
- Naturwissenschaften Biowissenschaften Virologie
- Wirtschaftswissenschaften Betriebswirtschaft Bereichsspezifisches Management Betriebliches Gesundheitsmanagement
Weitere Infos & Material
Introduction
Contributors ix
Foreword--Caryl P. Griffin and James Welch xiii
Preface xv
Section I. Hazard identification
1. The Microbiota of Humans and Microbial Virulence Factors 3
Paul A. Granato
2. Indigenous Zoonotic Agents of Research Animals 19
Lon V. Kendall
3. Biological Safety Considerations for Plant Pathogens and Plant-Associated Microorganisms of Significance to Human Health 39
Anne K. Vidaver, Sue A. Tolin, and Patricia Lambrecht
4. Laboratory-Associated Infections 59
Karen Brandt Byers and A. Lynn Harding
Section II. Hazard assessment
5. Risk Assessment of Biological Hazards 95
Dawn P. Wooley and Diane O. Fleming
6. Protozoa and Helminths 105
Barbara L. Herwaldt
7. Mycotic Agents 147
Wiley A. Schell
8. Bacterial Pathogens 163
Travis R. McCarthy, Ami A. Patel, Paul E. Anderson, and Deborah M. Anderson
9. Viral Agents of Human Disease: Biosafety Concerns 187
Michelle Rozo, James Lawler, and Jason Paragas
10. Emerging Considerations in Virus-Based Gene Transfer Systems 221
J. Patrick Condreay, Thomas A. Kost, and Claudia A. Mickelson
11. Biological Toxins: Safety and Science 247
Joseph P. Kozlovac and Robert J. Hawley
12. Molecular Agents 269
Dawn P. Wooley
13. Biosafety for Microorganisms Transmitted by the Airborne Route 285
Michael A. Pentella
14. Cell Lines: Applications and Biosafety 299
Glyn N. Stacey and J. Ross Hawkins
15. Allergens of Animal and Biological Systems 327
Wanda Phipatanakul and Robert A. Wood
Section III. Hazard Control
16. Design of Biomedical Laboratory and Specialized Biocontainment Facilities 343
Jonathan T. Crane and Jonathan Y. Richmond
17. Primary Barriers and Equipment-Associated Hazards 367
Elizabeth Gilman Duane and Richard C. Fink
18. Primary Barriers: Biological Safety Cabinets, Fume Hoods, and Glove Boxes 375
David C. Eagleson, Kara F. Held, Lance Gaudette, Charles W. Quint, Jr., and David G. Stuart
19. Arthropod Vector Biocontainment 399
Dana L. Vanlandingham, Stephen Higgs, and Yan-Jang S. Huang
20. Aerosols in the Microbiology Laboratory 411
Clare Shieber, Simon Parks, and Allan Bennett
21. Personal Respiratory Protection 425
Nicole Vars McCullough
22. Standard Precautions for Handling Human Fluids, Tissues, and Cells 443
Debra L. Hunt
23. Decontamination in the Microbiology Laboratory 463
Matthew J. Arduino
24. Packing and Shipping Biological Materials 475
Ryan F. Relich and James W. Snyder
Section IV. Administrative Control
25. Developing a Biorisk Management Program to Support Biorisk Management Culture 495
LouAnn C. Burnett
26. Occupational Medicine in a Biomedical Research Setting 511
James M. Schmitt
27. Measuring Biosafety Program Effectiveness 519
Janet S. Peterson and Melissa A. Morland
28. A ""One-Safe"" Approach: Continuous Safety Training Initiatives 537
Sean G. Kaufman
29. Biosafety and Biosecurity: Regulatory Impact 551
Robert J. Hawley and Theresa D. Bell Toms
Section V. Special Environments
30. Biological Safety and Security in Teaching Laboratories 565
Christopher J. Woolverton and Abbey K. Woolverton
31. Biosafety in the Pharmaceutical Industry 585
Brian R. Petuch
32. Biosafety Considerations for Large-Scale Processes 597
Mary L. Cipriano, Marian Downing, and Brian R. Petuch
33. Veterinary Diagnostic Laboratories and Necropsy 619
Timothy Baszler and Tanya Graham
34. Special Considerations for Animal Agriculture Pathogen Biosafety 647
Robert A. Heckert, Joseph P. Kozlovac, and John T. Balog
35. Biosafety of Plant Research in Greenhouses and Other Specialized Containment Facilities 665
Dann Adair, Sue Tolin, Anne K. Vidaver, and Ruth Irwin
36. Biosafety Guidelines for Working with Small Mammals in a Field Environment 679
Darin S. Carroll, Danielle Tack, and Charles H. Calisher
37. Components of a Biosafety Program for a Clinical Laboratory 687
Michael A. Pentella
38. Safety Considerations in the Biosafety Level 4 Maximum-Containment Laboratory 695
David S. Bressler and Robert J. Hawley
Index 719
