Buch, Englisch, Band 423, 300 Seiten, Paperback, Format (B × H): 178 mm x 254 mm, Gewicht: 598 g
Buch, Englisch, Band 423, 300 Seiten, Paperback, Format (B × H): 178 mm x 254 mm, Gewicht: 598 g
Reihe: Advances in Experimental Medicine and Biology
ISBN: 978-1-4684-6038-4
Verlag: Springer US
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
1. Examples of in Vitro-in Vivo Relationships with a Diverse Range of Quality.- 2. Dissolution Assay Development for in Vitro-in Vivo Correlations: Theory and.- 3. In Vitro Dissolution Profile Comparison and IVIVR: Carbamazepine Case.- 4. A General Framework for Non-Parametric Subject-Specific and Population Deconvolution Methods for in Vivo-in Vitro Correlation.- 5. Convolution-Based Approaches for in Vivo-in Vitro Correlation Modeling.- 6. Approaches to IVIVR Modelling and Statistical Analysis.- 7. Validation of in Vitro-in Vivo Correlation Models.- 8. Examples of Developing in Vitro-in Vivo Relationships.- 9. The Biopharmaceutic Drug Classification and Drugs Administered in Extended Release (ER) Formulations.- 10. Investigating in Vitro Drug Release Mechanisms Inside Dosage Forms: Monitoring Liquid Ingress in HPMC Hydrophilic Matrices Using Confocal Microscopy.- 11. Determination of Critical Manufacturing and Formulation Variables for a Hydrophilic Matrix Tablet Formulation Using an in Vitro Discriminatory Dissolution Method.- 12. Artificial Neural Network Based in Vitro-in Vivo Correlations.- 13. Setting Dissolution Specifications for Modified-Release Dosage Forms.- 14. Review of Methodologies for the Comparison of Dissolution Profile Data.- 15. Assessing Whether Controlled Release Products with Differing in Vitro Dissolution Rates Have the Same in Vivo-in Vitro Relationship.- 16. Comparison of Methodologies for Evaluating Regional Intestinal Permeability.- 17. In Vitro-in Vivo Relationships of Several “Immediate” Release Tablets Containing a Low Permeability Drug.- 18. Nonlinear in Vitro-in Vivo Correlations.- 19. Use of Nonlinear Mixed Effects Modelling in the Development of in Vitro-inVivo Correlations.- 20. The Development of a Novel in Vitro DiscriminatoryDissolution Method for a Class I Drug in a Matrix Tablet Formulation.- 21. In Vivo-in Vitro Evaluation of the Impact of Accelerated Stability Conditions on a Hydrophilic Matrix Tablet.- 22. Development of in Vitro-in Vivo Correlations Using Various Artificial Neural Network Configurations.- 23. Impact of IVIVR on Product Development.- 24. The Role of in Vitro-in Vivo Correlations (IVIVC) to Regulatory Agencies.- 25. Draft Guidance for Industry Extended-Release Solid Oral Dosage Forms: Development, Evaluation and Application of in Vitro-in Vivo Correlations.- 26. Issues Important to in Vitro-in Vivo Correlation: IVIVR Workshop Open Discussion.