Buch, Englisch, Band 2, 278 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 6083 g
Reihe: Healthy Ageing and Longevity
Buch, Englisch, Band 2, 278 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 6083 g
Reihe: Healthy Ageing and Longevity
ISBN: 978-3-319-14829-8
Verlag: Springer International Publishing
This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by these two interventions. The emphasis on epigenetics helps to illuminate the underlying mechanisms of anti-ageing interventions, as ageing and disease are predominately epigenetic phenomena.
Among the highlights are chapter-length discussion of such topics as: how anti-inflammatory action of calorie restriction underlies the retardation of ageing and age-related diseases (Chapter 3); epigenetic modification of gene expression by exercise (Chapter 5); the role of functional foods and their bioactive components in bone health (Chapter 8); and an account of the first decade of a study of calorie restriction in nonhuman primates, conducted by the National Institute on Ageing.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Ernährungsmedizin, Diätetik
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Wachstum, Entwicklung, Altern
Weitere Infos & Material
Preface.- Epigenetics and Nutrition.- Calorie restriction as a potent epigenetic modifier.- Anti-inflammatory action of calorie restriction for aging intervention.- Hormonal influence and modulation on aging.- Epigenetic modification by exercise.- Physiological bases and underlying mechanisms of exercise.- Sarcopenia and its intervention.- Nutritional impacts on osteopenia and osteoporosis.- Nutritional interventions for cardiac aging and age-related cardiovascular diseases.- Nutritional influence on aging brain.- Mechanistic bases of calorie restriction mimetics.- Lessons learned from calorie restricted non-human primate research.