Alouf / Freer | The Comprehensive Sourcebook of Bacterial Protein Toxins | Buch | 978-0-12-053075-5 | sack.de

Buch, Englisch, 650 Seiten, Format (B × H): 216 mm x 279 mm

Alouf / Freer

The Comprehensive Sourcebook of Bacterial Protein Toxins

Buch, Englisch, 650 Seiten, Format (B × H): 216 mm x 279 mm

ISBN: 978-0-12-053075-5
Verlag: Elsevier Science & Technology


The Comprehensive Sourcebook of Bacterial Protein Toxins, Second Edition, provides an up-to-date description of the great advances made in our understanding of the structure, genetics, cellular, and molecular mechanisms of action of bacterial protein toxins over the past decade. This work follows and expands on the first edition (published in 1991), with 70% totally new content and full-color illustrations. Molecular biology, microbiology, immunology, cell biology, protein engineering, structural biochemistry, and clinical research in infectious diseases are brought together to provide a complete overview of the field.
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Weitere Infos & Material


J.E. Alouf and J.H. Freer, Preface.
U. Dobrindt and J. Hacker, Plasmids, Phages, and Pathogenicity Islands: Lesson on the Evolution of Bacterial Toxins.
Toxins Acting on Cytosolic Targets:
P. Bouquet, The RAS Superfamily of Small GTP-Binding Proteins as Targets for Bacterial Toxins.
S. Olsnes, J. Wesche, and P.Ø. Falnes, Binding, Uptake, Routing, and Translocation of Toxins with Intracellular Sites of Action.
R.K. Holmes and J.G. Siekierke, Regulation of Diptheria Toxin Production.
T. Hirst, Cholera Toxin and E. Coli Heat-Labile Enterotoxins.
C. Locht and R. Antoine, Bordetella Pertussis Protein Toxins.
M. Thelestam, E. Chavez-Olarte, M. Moos, and C. von Eichel Streiber, Clostridial Toxins Acting on the Cytoskeleton.
M.R. Popoff and J.-C. Marvaud, Structural and Genomic Features of Clostridial Neurotoxins.
J. Herreros, G. Lalli, C. Montecucco, and G. Schiavo, Pathophysiological Properties of Clostridial Neurotoxins.
D.W.K. Acheson and G.T. Keusch, The Family of Shiga Toxins.
S.A. Leppla, The Bifactorial Bacillus Anthracis Lethal and Oedema Toxins.
C. Montecucco, E. Papini, M. de Bernard, J.R. Telford, and R. Rappuoli, Helicobacter Pylori Vacuolating Cytotoxin and Associated Pathogenic Factors.
Membrane-Damaging Toxins:
G. Menestrina and B.V. Semj(?)n, Biophysical Methods and Membrane Models for the Study of Bacterial Pore Forming Cytolysins.
R.W. Titball, Membrane Damaging and Cytotoxic Phospholipases.
A. Ludwig and W. Goebel, The Family of the Multigenic Encoded RTX Toxins.
V. Braun and R. Hertle, The Family of Serratia and Proteus Cytolsins.
J.T. Buckley, The Channel-Forming Toxin Aerolysin.
S. Shindoa, Vibrio Cholerae and Other Vibrio Species Haemolysins.
J. Dufourcq, S. Castano, and J.-C. Talbot, Toxin, d-Related Hemolytic Toxins and Peptide Analogues.
G. Prévost, Staphylococcal Bi-Component Leucotoxins.
M.S. Gilmore, M. Callegan, and B. Jett, Multicomponent Cytolysins of Enterococcus Faecalis and Bacillus Cereus.
R.K. Tweten and B.R. Sellman, Clostridium Septicum Pore-Forming and Lethal a-Toxin.
J.E. Alouf, The Family of the Cholesterol-Binding Cytolysins.
J.E. Alouf and M. Palmer, Streptolysin O (SLO).
T.J. Mitchell, Pneumolysin: Structure, Function, and Role in Disease.
J. Rossjohn, R.K. Tweten, J.I. Rood, and M. Parker, Perfringolysin O.
T. Jacobs, A. Darji, S. Weiss, and T. Chakraborty, Listeriolysin, the Thiol-Activated Hemolysin of Listeria Monocytogenes.
Other Toxins of Clinical, Pharmacologic, and Therapeutic Interest:
J.D. Dubreuil, Enterotoxigenic Escherichia Coli Heat-Stable Toxins.
T. Takeda, K.-I. Yoshino, T. Ramamurthy, and G.B. Nair, Heat-Stable Enterotoxins of Vibrio and Yersinia Species.
C.L. Sears, Bacteroides Fragilis Toxins.
J.E. Alouf, H. Müller-Alouf, and W. Köhler, Superantigenic Streptococcus Pyogenes Erythrogenic/Pyrogenic Exotoxins and Other Mitogens.
S.R> Monday and G.A> Bohach, Properties of Staphylococcus Aureus Enterotoxins and Toxic Shock Syndrome Toxin-1.
C. Carnoy and M. Simonet, Yersinia Pseudotuberculosis Superantigenic Toxins.
D.L. Stevens and A.E. Bryant, The Pathogenesis of Shock and Tissue Injury in Clostridia Gas Gangrene.
B. König, A. Drynda, A. Ambrosch, and W. König, Toxin-Induced Modulation of Inflammatory Processes.
Y. Piímont, Staphylococcal Epidermolytic Toxins.
P.E. Granum and S. Brynestad, Bacterial Toxins as Food Poisons.
J.C. VanderSpek and J.R. Murphy, Diphtheria Toxins-Based Interleukin 2 Fusion Proteins.
A.-M. Svennerholm and J. Holmgren, Toxin-Based Vaccines for Cholera and Escherichia Coli Diarrheas.


Joseph E. Alouf is Professor of Microbiology at the Pasteur Institute of Lille. He is former Head of the Department of Bacteriology and Mycology at the Pasteur Institute at Paris and Chairman of its Scientific Council. He served as Secretary General of the French Society of Immunology from 1984-1986 and President of the Federation of the European Microbiological Societies from 1989-1992. His 40-year research work relates to the field of bacterial protein toxins and immunology of infectious diseases. He is also the co-editor of several books.


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