Natural Hosts of Siv

Implication in AIDS
Erscheinungsjahr 2014
ISBN: 978-0-12-404734-1
Verlag: Elsevier Health Sciences

Buch, Englisch, 400 Seiten, Format (B × H): 240 mm x 408 mm, Gewicht: 815 g

Natural Hosts of SIV: Implications in AIDS thoroughly reviews the possible mechanisms by which African nonhuman primate natural hosts of lentiviruses remain essentially disease-free while other hosts exhibit disease and death. The book ultimately indicates directions for further research and potential translations of this compelling phenomenon into novel approaches to treat and prevent HIV. When Asian non-human primate non-natural hosts are experimentally infected with viruses isolated from African species, disease and death normally results. Meanwhile, these African nonhuman primate natural hosts maintain similar levels of plasma and cellular viremia and exhibit compellingly different, essentially disease-free, states. This work attempts to answer the question of how the natural host remains disease resistant.

Zielgruppe

<p>Academics in the field of HIV/SIV research who are studying mechanisms of pathogenesis, vaccinologists, virologists, immunologists, epidemiologists, geneticists, primatologists, pathologists, and public health experts.</p>

Autoren/Hrsg.

Ansari, Aftab A

Silvestri, Guido

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Public Health, Gesundheitsmanagement, Gesundheitsökonomie, Gesundheitspolitik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Medizinische Mikrobiologie & Virologie
• Naturwissenschaften Biowissenschaften Virologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin HIV, AIDS
• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Epidemiologie, Medizinische Statistik
• Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Wirbeltiere (Vertebrata) Säugetiere (Mammalia) Primaten

Inhaltsverzeichnis

1. Overview   Aftab Ansari and Guido Silvestri 2. Historical perspective   Preston Marx 3. SIV infections in the wild   Cristian Apetrei and Martine Peeters 4. Virology of SIVs   Frank Kirchhoff 5. SIV infection of chimpanzees   Jonathan Heeney, Edward James Donald Greenwood and Fabian Schmidt 6. Pathology of acute & chronic infection   Francois Villinger and Sanjeev Gumber 7. Mucosal immunity   Jason Brenchley 8. Innate immunity   Steven E. Bosinger and R. Keith Reeves 9. Humoral immune responses   Cynthia Ann Derdeyn and Reinhard Kurth 10. Cellular immune responses   Amitinder Kaur 11. Chronic immune activation   Donald Sodora 12. Pattern of infected cells   Mirko Paiardini and Thomas Howerton Vanderford V 13. Viral transmission   Ivona Pandrea and Ann Chahroudi 14. Genetics of the host   Lutz Walter 15.  The different modes of HIV/SIV control in monkeys and humans   Lisa Chakrabarti 16. Humans resembling natural hosts   Amalio Telenti and Paul McLaren Epilogue: Implications for HIV infection   Aftab Ansari and Guido Silvestri

Über Autor(innen)

Ansari, Aftab A
Aftab Ansari, Ph.D.
Dr. Aftab A. Ansari, Professor, Department of Pathology and Laboratory Medicine, Room 2309 WMB, Emory University School of Medicine, 101 Woodruff Circle, Atlanta, GA 30322, USA

Ph.D., University of Arizona, Tucson, Arizona, 1970
M.S., University of California, Los Angeles, CA, 1967
M.S., University of Karachi, Karachi, Pakistan, 1963
B.S., University of Karachi, Karachi, Pakistan, 1961
1981-present Senior Consultant, Naval Medical Research and Development Command, Bethesda, Maryland
1985-Present Professor, Department of Pathology and Laboratory Medicine, Emory University
1999-present Scientific Advisor, U.S. Naval Medical Research Unit #2, Jakarta, Indonesia.
2002-present Scientific Advisory Board, One World Health, San Francisco, CA.
2001-2008 Scientific Advisory Board, Lipid Sciences, Inc. Pleasanton, CA.
2005-present Scientific External Advisory Board member, CAHDR, Meharry Medical College,
Nashville, TN
2008-present Scientific Advisory Board, SMART Technologies, Inc., Rehovot, Israel
2007-present Member, FDA Expert Panel, FDA Center for Devices and Radiological Health
(CDRH), SGE, Deptt. Of Health & Human Services, Immunology Devices Panel

Silvestri, Guido
Professor Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA
Chief, Division of Microbiology and Immunology, Yerkes National Primate Research Center
Georgia Research Alliance Eminent Scholar in Comparative Pathology, Emory University