Buch, Englisch, 137 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 242 g
Evidence-Based Perspectives from Molecular Biology to Systems Biology
Buch, Englisch, 137 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 242 g
ISBN: 978-1-4899-9946-7
Verlag: Springer
This monograph arises from observations that have suggested that the skeletal system and the immune system are intimately intertwined. Chronic inflammatory reactions subsequent to an excessive immune reaction can damage the bones, as in rheumatoid arthritis (RA), osteoporosis, patients seropositive for the human immunodeficiency virus (HIV)-1 and with signs and symptoms of the acquired immune deficiency syndrome (AIDS), and bone cancer. Bones – in particular the bone marrow – are one of the primary locations in which cells of the immune system mature.
In brief, this monograph begins to answer a range of questions, such as, what is osteoimmunology all about?, does the immune system and its components affect bone development?, how do stress hormones impact upon the pathophysiology of bone-immune interactions?, can the scientific process of research synthesis, obtain the best available evidence for treatment of diseases involving the bone-immune entity (i.e., osteo immunopathologies) means of evidence-based clinical decision-making directed at the treatment of osteoimmune pathologies?
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Infektionskrankheiten
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pathologie, Cytopathologie, Histopathologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Medizinische Mikrobiologie & Virologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
Weitere Infos & Material
Part 1: Fundamentals.- Osteoimmunology: Introduction to a new field.- Immunobiology.- Bone metabolism.- The Osteoimmune system: RANK-RANKL (et all).- Part II: Clinical & Translational Research.- Clinical & Translational research – Fundamental Principles.- Evidence-Based Research in Osteoimmunology.- Evidence-Based Clinical Osteoimmune Practice.- Special population * Problems-Based Osteoimmunology.- Part III: Challenges for the Future.- Biomarkers.- Epigenetic and Chromatin Regulation in Osteoimmune Regulation.- Stem Cells Niches and Osteoimmune Microenvironments.- Techniques & Protocols.-