Autophagy in Immune Response: Impact on Cancer Immunotherapy

Erscheinungsjahr 2020
ISBN: 978-0-12-819609-0
Verlag: William Andrew Publishing

Buch, Englisch, 242 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 660 g

Autophagy in Immune Response: Impact on Cancer Immunotherapy focuses on the status and future directions of autophagy with respect to different aspects of its interaction with the immune system and immunotherapy. The book takes scientific research in autophagy a step further by presenting reputable information on the topic and offering integrated content with advancements in autophagy, from cell biology and biochemical research, to clinical treatments. This book is a valuable source for cancer researchers, oncologists, graduate students and several members of biomedical field who are interested in learning more on the relationship between autophagy and immunotherapies.

Zielgruppe

Cancer researchers, medical scientists, clinicians, graduate students

Autoren/Hrsg.

Chouaib, Salem

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung

Inhaltsverzeichnis

1. Signaling pathways that control autophagy2. Autophagosome biogenesis3. Autophagy in T and B cell homeostasis: Recycling for sustainable growth4. Autophagy is involved in quality/quantity control of organelles and their homeostasis5. Role of autophagy in immune regulation6. Autophagy in natural and therapy-driven anticancer immunosurveillance7. Autophagy and resistance to cell-mediated cytotoxicity8. Autophagy and metabolism9. Autophagy in connecting immunity and metabolism10. Autophagy in tumor cell migration and invasion, tumor stem cell maintenance and therapy resistance11. Autophagy during Early Virus-Host Cell Interactions12. Diverse roles for autophagy in impeding and promoting tumorigenesis13. The autophagic network and cancer14. Targeting Autophagy in the Tumor Microenvironment15. Autophagy and microbiota16. Regulation of autophagy and mitochondrial dynamics17. Autophagy proteins in cell defenses and role in bacteria-macrophage interaction18. Autophagy, a key player in leukemogenesis and a therapeutic target in hematopoietic malignancies19. Autophagy in Cancer and Cancer Therapy20. Autophagy in the Tumor or in the Host: Which Plays a Greater Supportive Role?21. Autophagy and cancer therapy22. Therapeutic potential of autophagy modulation in the clinic23. Rationale and current approaches for developing autophagy inducers in medicine24. Autophagy and metabolism

Über Autor(innen)

Chouaib, Salem
Dr. Salem Chouaib earned his Ph.D. in Immunology from the University of Pierre and Marie Curie (Paris VI) in 1983. He completed postdoctoral training at Memorial Sloan Kettering Cancer Center before joining INSERM and Institut Gustave Roussy, where he became Research Director and led the Tumor Immunology Lab. His research explores killer cell reactivity and tumor microenvironment dynamics, with a focus on hypoxia's role in immune resistance. A pioneer in cancer immunotherapy, he founded the Thumbay Research Institute for Precision Medicine. Dr. Chouaib has received prestigious awards, including the French League Against Cancer Prize and the Presidential Prize in Biotechnology. He has mentored numerous postdocs, lectures at University Paris-Sud, and has published over 350 scientific works. He also serves as a guest lecturer, journal referee, and scientific advisor globally.