The Molecular and Cellular Biology of Wound Repair

1996
ISBN: 978-0-306-45159-1
Verlag: Springer US

Buch, Englisch, 612 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 1109 g

'Provides comprehensive detail on the various aspects of particular molecules involved in the phases of injury and repair and the cellular movements and processes....This is an excellent reference book for libraries serving biology and health science clientele and for workers in this field of research.' -, from a review of the First Edition All chapters of this second edition have been completely revised and expanded-especially the chapters on growth factors and extracellular matrix molecules. discuss provisional matrix proteins, extracellular matrix receptors, and scarring versus nonscarring wound healing.

Zielgruppe

Research

Autoren/Hrsg.

Clark, R. A. F.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete AINS Notfallmedizin & Unfallmedizin (inkl. Notdienste)
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Botanik

Inhaltsverzeichnis

I. Preliminaries.- 1 Wound Repair: Overview and General Considerations.- 2 Provisional Matrix.- 3 Macrophage Involvement in Wound Repair, Remodeling, and Fibrosis.- 4 Resolution of Inflammation.- II. Growth Factors in Soft Tissue Healing.- 5 Epidermal Growth Factor and Transforming Growth Factor-?.- 6 Modulation of Wound Repair by Members of the Fibroblast Growth Factor Family.- 7 Role of Platelet-Derived Growth Factor in Vivo.- 8 Transforming Growth Factor-?.- III. New Tissue Formation: The Cutaneous Paradigm.- 9 Integrins in Wound Repair.- 10 Reepithelialization.- 11 Angiogenesis.- 12 Mechanisms of Parenchymal Cell Migration into Wounds.- 13 The Role of the Myofibroblast in Wound Healing and Fibrocontractive Diseases.- IV. Essentials of Tissue Remodeling.- 14 Proteinases and Tissue Remodeling.- 15 Proteoglycans and Their Role in Wound Repair.- 16 Collagens and the Reestablishment of Dermal Integrity.- 17 The Dermal-Epidermal Basement Membrane Zone in Cutaneous Wound Healing.- 18 Fetal Wound Healing and the Development of Antiscarring Therapies for Adult Wound Healing.