Dumitrescu / Verma | Cancer Epigenetics for Precision Medicine | Buch | sack.de

Dumitrescu / Verma Cancer Epigenetics for Precision Medicine



Methods and Protocols

Softcover Nachdruck of the original 1. Auflage 2018, Band: 1856, 298 Seiten, Kartoniert, Previously published in hardcover, Format (B × H): 177 mm x 254 mm, Gewicht: 599 g Reihe: Methods in Molecular Biology
ISBN: 978-1-4939-9383-3
Verlag: Springer, Berlin


Dumitrescu / Verma Cancer Epigenetics for Precision Medicine

This volume discusses certain epigenetic changes recognized in early carcinogenic lesions and different tumors, as well as factors that alter the epigenome and epigenetic profile such as diet, alcohol, immunity, circadian rhythm, and more. The chapters in this book further delve into this field and cover topics such as epigenome-based precision medicine in lung cancer; interplay between genetic and epigenetic changes in breast cancer subtypes; genetic regulation of PDCD1 gene in cancer immunology; and pyrosequencing methylation analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and authoritative, Cancer Epigenetics for Precision Medicine: Methods and Protocols is a valuable resource to help researchers and scientists identify these specific biomarkers and work towards the prevention, diagnosis, and prognosis of different cancers in the future.

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Professional/practitioner

Weitere Infos & Material


Preface...Table of Contents...Contributing Authors...
Part I Early Epigenetic Changes and New Epigenetic Targets in Different Types of Cancers
1.Early Epigenetic Markers for Precision MedicineRamona G. Dumitrescu
2.Interplay between Genetic and Epigenetic Changes in Breast Cancer SubtypesRamona G. Dumitrescu
3.Role of Microbiome in Carcinogenesis Process and Epigenetic Regulation of Colorectal CancerLulu Farhana, Hirendra N. Banerjee, Mukesh Verma, and Adhip PN Majumdar
4.Epigenome-Based Precision Medicine in Lung CancerDong Hao Jin and Duk-Hwan Kim
5.Epigenetics in Hematological Malignancies N. Cruz-Rodriguez, AL Combita, and J. Zabaleta
6.MicroRNAs Role in Prostate CancerOvidiu Balacescu, Ramona G. Dumitrescu, and Catalin Marian
Part II Contributing Environmental Factors to Epigenetic Changes Leading to Cancer Development
7.The Effects of Dietary Nutrients on Epigenetic Changes in CancerNicoleta Andreescu, Maria Puiu, and Mihai Niculescu
8.Diet, Microbiome, and Epigenetics in the Era of Precision MedicineGabriela Riscuta, Linda Duffy, Dan Xi, Dudith Pierre-Victor, Pamela Starke-Reed, and Jag Khalsa
9.Alcohol-Induced Epigenetic Changes in CancerRamona G. Dumitrescu
10.Epigenetic Basis of Circadian Rhythm Disruption in CancerEdyta Reszka and Shanbeh Zienolddiny
11.Epigenetic Changes of the Immune System with Role in Tumor DevelopmentIrina Daniela Florea and Christina Karaoulani
12.DNA Methylation as a Biomarker of Aging in Epidemiologic StudiesUnhee Lim and Min-Ae Song
13.Challenges and Opportunities in Social Epigenomics and CancerKrishna Banaudha, Vineet Kumar, and Mukesh Verma 
Part III Methods Used in Cancer Epigenomics 
14.Epigenetic and Genetic Regulation of PDCD1 Gene in Cancer ImmunologyAlok Mishra and Mukesh Verma 
15.Methylation and Micro RNA Profiling to Understand Racial Disparities of Prostate CancerHirendra Nath Banerjee, William Kahan, Vineet Kumar, and Mukesh Verma
16.Analysis of DNA Hypermethylation in Pancreatic Cancer using Methylation Specific PCR and Bisulfite SequencingBin Liu and Christian Pilarsky
17.Pyrosequencing Methylation AnalysisMatthew Poulin, Jeffrey Y. Zhou, Liying Yan, and Toshi Shioda


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