E-Book, Englisch, 200 Seiten, eBook
Grassi / Travis / Casali Biochemistry of Pulmonary Emphysema
1992
ISBN: 978-1-4471-3771-9
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark
E-Book, Englisch, 200 Seiten, eBook
Reihe: Current Topics in Rehabilitation
ISBN: 978-1-4471-3771-9
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark
Pulmonary emphysema is a disease which develops because of a localized imbalance between endogenous proteinase inhibitors and proteinases leaking from neurophils during phagocytosis at inflammatory foci within the lung. This volume not only reviews at a biochemical level what is known about the natural inhibitors and proteinases involved in connective tissue destruction within the lung, but also suggests novel methodologies for reestablishing proper enzyme-inhibitor balance, including the use of natural or synthetic inhibitors for supplementation or gene therapy.
Zielgruppe
Research
Weitere Infos & Material
From the Contents: Pulmonary Emphysema: What's going on.- Elastin and the Lung.- An Introduction to the Endopeptidases.- Lung Proteinase and Emphysema.- Multiple Functions of Neutrophil Proteinases and their Inhibitor Complexes.- Kinetics of the Interaction of Human Leucocyte Elastase with Protein Substrates.- Proteinase Inhibitor Candidates for Therapy of Enzyme-Inhibitor Imbalances.- Antileucoprotease (Secretory Leucocyte Proteinase Inhibitor), A Major Proteinase Inhibitor in the Human Lung.- Development and Evaluation of Antiproteases as Drugs for Preventing Emphysema.- Genetic Control of Human Alpha-1-Antitrypson and Hepatic Gene Therapy.- Neutrophils, Neutrophil Elastase and the Fragile Lung.
