Buch, Englisch, 180 Seiten, Format (B × H): 156 mm x 234 mm
Biochemical and Medical Consequences
Buch, Englisch, 180 Seiten, Format (B × H): 156 mm x 234 mm
ISBN: 978-1-032-82445-1
Verlag: Taylor & Francis Ltd
Repeat amino acid sequences are important in protein structure, disorder, function and evolution. Repeats of some amino acids exist in proteomes across species.
This volume highlights:
- Which repeat sequences have pathogenic consequences and why?
- Repeats which lead to surface hydrophobic clusters and their importance
- Role of aromatic amino acid clusters in protein-protein and protein-drug interactions
- Cell-penetrating peptides and Elastin-like peptides
- Unusual phenomenon of fluorescence observed with repeats of some non-aromatic amino acids
- The use of residue cluster classes to represent protein structure and model structure-function relationships.
Zielgruppe
Academic and Postgraduate
Autoren/Hrsg.
Fachgebiete
- Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Verfahrenstechnik, Chemieingenieurwesen
- Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
- Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
Weitere Infos & Material
Preface. 1. Pathogenic Role of Repeat Polypeptides in Repeat Expansion Diseases. 2. Pathologies Due to PolyQ Sequences. 3. Importance of Surface Hydrophobic Clusters in Proteins. 4. Residue Cluster Classes in Protein-Protein Interactions. 5. Aromatic Clusters in Proteins: Folding, Drug Interactions and Protein-Protein Complexes. 6. Cell Penetrating Peptides with Repeat Sequences of Amino Acids. 7. Recent Advances and Applications in Self-Assembling Short-Chain Elastin-Like Peptide Analogs. 8. Unconventional Fluorescence Properties of Non-aromatic Amino Acids: Material and Biological Applications. Index.