MR Linac Radiotherapy

A New Personalized Treatment Approach
Erscheinungsjahr 2022
ISBN: 978-0-323-91689-9
Verlag: William Andrew Publishing

Buch, Englisch, 516 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 450 g

MR Linac Radiotherapy: A New Personalized Treatment Approach comprises both clinical and physical aspects of this new technology. The book covers treatment planning, workflow and technical issues about MR-Linac. Specially, the clinical use of MR-Linac according to different cancer types is presented by experienced physicians. This is a unique guide for medical physicists, RTTs, dosimetrists and physicians, as well as radiation oncologists and their teams. The MR Linac combines two technologies - a magnetic resonance imaging scanner and a linear accelerator - to precisely locate tumors, tailor the shape of radiation beams in real-time, and precisely deliver doses of radiation, even to moving tumors.

This highly innovative technology is very new, and the number of newly installed MR-Linac machines will gradually increase worldwide. However, as there is no published book as a guideline, this book will help new MR-Linac users and centers planning to have MR-Linac.

Autoren/Hrsg.

Hackett, Sara L.

Onal, Cem

Ozyar, Enis

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Bildgebende Verfahren, Nuklearmedizin, Strahlentherapie Nuklearmedizin, PET, Radiotherapie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung

Inhaltsverzeichnis

1. History of development of MR-Linac

2. Basics of MR imaging for radiation oncologist -

3. MR safety for MR guided RT

4. Technical concept of current clinical MR-Linacs

5. Immobilization systems in MR guided RT

6. Use of MR-Linac as a simulator for radiotherapy department

7. Simulation workflow in MR guided RT

8. Patient reported outcomes in MR guided RT

9. Contrast use in MR guided RT

10. Treatment workflow steps in MR guided adaptive RT

11. Changing role of RTTs in MR guided RT

12. Role of MR-linac in management of brain tumors and brain metastasis

13. The role of adaptive RT in head and neck cancers and future perspective for MR guided RT

14. Use of MR-linac in peripheral and central lung tumors and metastasis

15. Current role and future perspectives in breast cancer treatment with MR-linac

16. Role of MR guided RT in management of liver tumors and metastases

17. Dose escalation in SBRT of pancreatic cancer using adaptive online RT

18. Hypofractionation and MR guided RT in management of prostate cancers

19. Use of MR-linac in management of locally recurrent prostate cancer

20. Potential role of Mr guided RT in pediatric cancers

21. Role of MR-linac in management of bone or lymph node oligometastasis

22. Future clinical use of MR-Linac.

22. Use of AI in MR-linac workflow
23. Role of radiomics in MR guided RT

Über Autor(innen)

Onal, Cem
Prof. Cem Onal is the founder and Chair of the Radiation Oncology Department at Baskent University. Prof. Onal completed his residency in radiation oncology in 2004 at Hacettepe University School of Medicine in Ankara. His primary research interests are prostate cancer, breast cancer, and gynecological malignancies. He has extensive experience using intensity modulated radiotherapy and image guided radiotherapy to treat prostate cancer, as well as brachytherapy for gynecological tumors, stereotactic radiotherapy, and radiosurgery. He is the director of the MR-Linac unit and has extensive experience treating prostate cancer and abdominal tumors with MR-Linac. He is also skilled in computed tomography-guided brachytherapy, intensity modulated radiotherapy, image-guided radiotherapy, stereotactic body radiotherapy/radiosurgery, and helical tomotherapy.
He has over 150 articles published in international and national journals. He has also presented over 350 international and national abstracts at various scientific meetings. He serves as the editorial board member and peer reviewer in several journals.

Hackett, Sara L.
Sara Hackett completed her B.Sc. (Hons) in Physics and Mathematics at the University of Western Australia in 2003, was awarded a Ph.D. with Distinction in 2008 by the same institute. She trained as a Medical Physicist, specializing in Radiotherapy, and received her certification in 2010. During this period she also completed an M.Sc. in Medical Physics with the Royal Melbourne Institute of Technology. After working as a postdoctoral fellow at the Université catholique de Louvain and the University of Oxford, she joined the Experimental Medical Physics group at University Medical Center Utrecht (UMCU) as a postdoctoral physis fellow to work on the clinical introduction of the MR-linac.

Dr. Hackett now works as a clinical physicist at UMCU with the primary responsibility for treatment planning. The Radiotherapy department has three MR-linacs, as well as ten Agility linacs. She is involved with lung radiotherapy on the MR-linac and is supervising M.Sc. and Ph.D. students in the development of gating, tracking and real-time-adapted radiotherapy.

Ozyar, Enis
Enis Ozyar M.D., graduated from Ankara University, Medical School, Ankara, Turkey in 1985 and finished his residency at Hacettepe University, School of Medicine, Department of Radiation Oncology, Ankara in 1993. He worked at the same department between 1993-2008. He obtained his associate professorship degree in 1998 and professorship degree in 2003. He was appointed as Chair and Professor of Radiation Oncology at the Acibadem MAA University, School of Medicine, Department of Radiation Oncology, Istanbul, Turkey in 2008.

Dr. Ozyar currently works at flaghship hospital - Acibadem Maslak Hospital - of the Acibadem Health Group (AHG). AHG is the largest private health care group in Turkey and have 8 Radiation Oncology centers equipped with high tech systems such as MRIdien Mr-Linac, IGRT-IMRT-SRT linac systems, robotic linacs, Gammaknife, brachytherapy and intraoperative radiotherapy. Dr. Ozyar is also working as coordinator of Radiation Oncology Centers of AHG. He is also charing Acibadem RTT school and Health Physics programme of Acibadem MAA University.

His main interest areas are head and neck cancer, prostate cancer, gynecological cancers, sterotactic radiotherapy and MR guided radiotherapy.

Dr. Ozyar published more than 100 manuscripts published in international SCI journals. His h-index is 27.