Transplantation of Composite Tissue Allografts

2008
ISBN: 978-1-4899-8807-2
Verlag: Springer US

Buch, Englisch, 483 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 756 g

This brilliant synthesis summarizes all of the recent accomplishments – as well as the ongoing research – in the field of composite tissue transplantation. It includes sections on hand transplantation and vascularized bone marrow transplantation. The volume focuses on immunology and the biotechnology/bioengineering aspects of transplantation surgery, as those two areas have demonstrated the most growth within the last five years in terms of current research.

Zielgruppe

Research

Autoren/Hrsg.

Hewitt, Charles W.

Lee, W. P. Andrew

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Chirurgie Transplantationschirurgie

Inhaltsverzeichnis

Section I.- The Establishment of Composite Tissue Allotransplantion as a Clinical Reality.- The Evolution of Composite Tissue Allotransplantation: the Twentieth Century Realization of “Cosmas and Damian”.- The Impact of the Discovery of Cyclosporine on Transplantation of Composite Tissue Allografts.- The First Limb Transplants with Cyclosporine.- Section II.- Translational Research in Composite Tissue Allotransplantation.- Relative Antigenicity of Allograft Components and Differential Rejection.- On the Road to Tolerance Induction in Composite Tissue Allotransplantation.- Donor-Specific Tolerance.- Immune Tolerance Induction: Basic Concepts for Composite Tissue Allotransplantation.- Section III.- Allograft Survival with Calcineurin Inhibitors.- Long-Term Prevention of Rejection and Combination Drug Therapy.- Locoregional Immunosuppression in Composite Tissue Allografting.- New Approaches to Antibody Therapy.- Section IV.- World Experience of Hand Transplantation-Independent Assessment.- Hand Transplantation: Lyon Experience.- Hand Transplantation: The Louisville Experience.- Hand Transplantation: The Innsbruck Experience.- Section V.- Vascularized Bone Marrow Transplantation.- Vascularized Bone Marrow Transplantation: Pathology of Composite Tissue Transplantation-Induced Graft-Versus-Host-Disease.- Immune Cell Redistribution After Vascularized Bone Marrow Transplantation.- Section VI.- Vascularized Knee Transplantation.- Tracheal Transplantation.- Laryngeal Transplantation.- Face Transplantation.- The Role of Allografts in Lower Extremity Reconstruction.- Skin Allografts in Scalp Reconstruction.- Abdominal Wall Transplantation.- Peripheral Nerve Allotransplantation.- Live-Donor Nerve Transplantation.- Section VII.- Ethical and Policy Concerns of Hand/Face Transplantation.- Ethical Debate on Human Face Transplantation.- Psychosocial Issues in Composite Tissue Allotransplantation.- Composite Tissue Transplantation in the Twenty-First Century.