Buch, Englisch, 588 Seiten, Format (B × H): 220 mm x 287 mm, Gewicht: 1851 g
Buch, Englisch, 588 Seiten, Format (B × H): 220 mm x 287 mm, Gewicht: 1851 g
Reihe: Foundations of Biochemistry and Biophysics
ISBN: 978-1-4200-8972-1
Verlag: CRC Press
Quantitative Understanding of Biosystems: An Introduction to Biophysics focuses on the behavior and properties of microscopic structures that underlie living systems. It clearly describes the biological physics of macromolecules, subcellular structures, and whole cells, including interactions with light.
Providing broad coverage of physics, chemistry, biology, and mathematics, this color text features:
Mathematical and computational tools—graphing, calculus, simple differential equations, diagrammatic analysis, and visualization tools
Randomness, variation, statistical mechanics, distributions, and spectra
The biological micro- and nanoworld—structures, processes, and the physical laws
Quantum effects—photosynthesis, UV damage, electron and energy transfer, and spectroscopic characterization of biological structures
Through its active learning approach, the text encourages practical comprehension of the behavior of biosystems, rather than knowledge of the latest research. The author includes graph- and diagram-centered physics and mathematics, simple software, frequent checks of understanding, and a repetition of important ideas at higher levels or from different points of view. After completing this book, students will gain significant computational and project experience and become competent at quantitatively characterizing biosystems.
CD-ROM Resource
The accompanying CD contains multimedia learning tools, such as video clips and animations, that illustrate intrinsically dynamic processes. For students inexperienced in the application of mathematics and physical principles to naturally occurring phenomena, this multimedia component emphasizes what is most obvious about biological systems: living things move. Students can also manipulate and re-program the included Excel graphs.
Zielgruppe
Advanced undergraduate and graduate students in physics, chemistry, biology/biochemistry, and biomedical engineering; advanced undergraduate students in applied math.
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
INTRODUCTION, APPROACH, AND TOOLSIntroduction to a New World Biological and Nonliving Worlds Contrasted Hierarchical Structure and Function Some Important Quantities to Get Started Biophysics and Biochemistry Operate in Water (Water 1) Important or "Hot" Issues in Biophysics, or How to Be Out-of-Date Quickly Is There a Career Here Somewhere? Read Appendix A
How (Most) Physicists Approach Biophysics Dealing with Nonspherical Cows: Drive for Simplicity Two Approaches to BiosystemsComparison of "Physics" and "Biology" Approaches to OrganismsMemorization: Its Advantages and Dangers
Math Tools: First Pass What Math Do We Need? Notation: Mathematics vs. Physics Notations ApproximationsVectors Two- and Three-Dimensional GeometryCalculusDifferential EquationsDistributions
STRUCTURE AND FUNCTIONWater IntroductionStructureUnusual Physical PropertiesSummary of Important Physical Properties Bulk vs. Local Structures Diffusion and Chemical Reactions in Water Solutes and the Solvent Power of Water Points to Remember
Structures: From 0.1 to 10 nm and LargerSoftware to Display and Analyze Biological Structures Solvents Small MoleculesMedium-Sized Molecules: Components of Large BiomoleculesForces and Free Energies BiopolymersMacromolecules: When Does a Molecule Become a Macroscopic Object?Points to Remember
First Pass at Supramolecular Structures: Assemblies of Biomolecules Measuring Properties of Three-Dimensional AggregatesSmall AggregatesLarge AggregatesTwo-Dimensional Aggregates: MembranesPoints to Remember
Putting a Cell Together: Physical Sketch Minimal, Prokaryotic, and Eukaryotic CellsPhysiology: Selective OverviewReproduction, DNA, and the Cell NucleusSensors and Recognition: Responding to the Outside World without Eyes
BIOLOGICAL ACTIVITY: QUANTUM MICROWORLDQuantum Primer Quantum Glossary Schrödinger Equation and Other Tools of Quantum MechanicsPauli Exclusion Principle From Atoms to Molecules Collisions of Atoms and Molecules Classical vs. Quantum: Is a 1-mm-Long Molecule of DNA a Quantum Object?Points to Remember
Light and Life Light: Our Energy Source Crucial Differences between One 5-eV and Two 2.5-eV Photons Properties of PhotonsScattering and RefractionAbsorption SpectraEmission SpectraEinstein Relations between Absorption and Emission of Atoms (Graduate Section)Intersystem Crossing: Singlets (S = 0) to Triplets (S = 1) Energy Transfer (FRET) Points to Remember
Photosynthesis Global Numbers Overall ProcessStructural Organization of Photosynthetic Units Light-Harvesting (Antenna) Proteins: Arrays of AbsorbersReaction Centers and Charge Separation: Purple Bacteria and CyanobacteriaArtificial Models and Nonpolluting Energy Production Points to Remember
Direct Ultraviolet Effects on Biological Systems Types and Sources of UV LightDivisions of the UV for Health Purposes: UV-A, UV-B, and UV-C UV Damage to Organisms: "Action Spectra" Wavelength-Dependent Photochemical Yields and Protein Damage UV Damage to DNAOptical Properties of the Skin SunscreensPoints to Remember
BIOLOGICAL ACTIVITY: (CLASSICAL) MICROWORLDMechanics and Dynamics Conservation Laws, Newton’s Laws, Forces, and Torques Friction: Familiar and Less Familiar Examples of Motion Gravitational Forces Volume Changes and Compressibility Stress and Strain Force of Friction, Dissipation, Inertia, and DisorderFluids and TurbulencePoints to Remember
Random Walks, Diffusion, and Polymer Conformation Review of Kinetic Theory of Gases: Implications for Biomolecular Averaging One-Dimensional Random Walk: Probabilities and Distributions Spreadsheet Model for a One-Dimensional Random WalkThree-Dimensional Random WalkDiffusion in the BulkReprise of Photosynthetic Light Harvesting Biopolymers—A Random ReprisePoints to Remember
Statistical Physics and Thermodynamics Primer Important Quantities: Temperature, Pressure, Density, and Number Statistical Mechanical View and DistributionsEquipartition of Energy"Internal" Energy: Kinetic (K) and Potential (U)Heat, Internal Energy, Work, and Enthalpy Conservative and Nonconservative Forces: DNA Example Ideal Gas Law Entropy: Gas