G Protein-Coupled Receptors

Softcover Nachdruck of the original 1. Auflage 1995
ISBN: 978-3-662-21932-4
Verlag: Springer

Buch, Englisch, 183 Seiten, Paperback, Format (B × H): 178 mm x 254 mm, Gewicht: 387 g

Reihe: Molecular Biology Intelligence Unit

This book is about the recent advances in the structural and functional characterization of receptors that influence intracellular signalling events through interaction with intracellular GTP-binding proteins (G proteins). Molecular cloning of members of the G protein-coupled receptor superfamily has complemented pharmacological investigations in providing a realization of the structural and functional diversity of these receptors. An increased understanding of the involvement of particular receptor subtypes in normal and pathophysiological processes represents exciting possibilities for the development of highly specific and effective therapeutic agents.

Zielgruppe

Research

Autoren/Hrsg.

Iismaa, Tiina P.

Shine, John

Biden, Trevor J.

Fachgebiete

• Naturwissenschaften Biowissenschaften Zellbiologie

Inhaltsverzeichnis

1. Cell Surface Receptors and the G Protein-Coupled Receptor Superfamily.- 2. Signaling Through G Protein-Coupled Receptors.- 3. Structural Determinants of Receptor Function.- 4. G Protein-Coupled Receptors, Pathology and Therapeutic Strategies.- 5. Future Prospects.