Tumor Infiltrating B Lymphocytes: A Novel Approach for Cancer Diagnostics and Therapeutics

A Novel Approach for Cancer Diagnostics and Therapeutics
1. Auflage 2020
ISBN: 978-0-387-69881-6
Verlag: Springer-Verlag New York Inc.

Buch, Englisch, 160 Seiten, Book, Format (B × H): 155 mm x 235 mm

The urgent need for the development of early tumor diagnosis and effective anti-tumor therapies remains. This work intends to provide a relatively broad audience with a novel approach for the development of cancer diagnostics and targeted therapeutics, based on recently proved hypotheses. It provides coverage of the most important aspects of a selected domain of tumor immunology, namely the characteristics and potential capacity of the tumor infiltrating B lymphocytes.

Zielgruppe

Research

Autoren/Hrsg.

Kotlan, Beatrix

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Medizinische Mikrobiologie & Virologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien

Inhaltsverzeichnis

Chapter 1. Tumor infiltrating T lymphocytes: Brief summary about the characteristics and role of tumor infiltrating T lymphocytes.Chapter 2. Tumor infiltrating B lymphocytes: Characteristics, potential capacity and role of tumor infiltrating B lymphocytes.Chapter 3. B lymphocytes in different solid tumors: Melanomas, breast carcinomas, ovarian carcinomas, neuroblastomaChapter 4. Results of immunoglobulin repertoire analysis: Fetal and adult normal B cells compared to B cells from tumor tissues.Chapter 5. Potential capacity of natural human antibodies for therapeutic approachesChapter 6. Potential capacity of autoantibodies for therapeutic approachesChapter 7. Potential capacity, benefits and drawbacks of different antibody fragments for therapeutic approachesChapter 8. Methodological arsenal of antibody engineering and biotechnology for developing novel immunoconjugates for diagnostics and therapeutics.Chapter 9. The secret of tumor infiltrating lymphocytes: novel tumor-specific target antigens revealed.Chapter 10. The "sleeping beauty" might be awaked: A special family of tumor associated molecules, the gangliosides.Chapter 11. Achievements and future prospects for novel tumor diagnostics and therapeuticsChapter 12. The benefits of targeted therapeutics to defeat cancer.