Monoamine Oxidase Inhibitors in Neurological Diseases

1. Auflage 1994
ISBN: 978-0-8247-9082-0
Verlag: CRC Press

Buch, Englisch, Band 21, 400 Seiten, Format (B × H): 163 mm x 235 mm, Gewicht: 649 g

Reihe: Neurological Disease and Therapy

Emphasizing the role of monoamine oxidase (MAO) in the etiology and pathogenesis of Parkinson's disease and Alzheimer's disease, this up-to-date reference describes the genetics, physiology, biochemistry, pharmacology, and clinical aspects of this very important class of enzymes.Details how the interaction between selegiline (deprenyl) and MAO may retard the progression of neurodegenerative disorders!Providing the latest theories on how selegiline operates, Monoamine Oxidase Inhibitors in Neurological Diseases presents fundamental information on MAO types A and B examines the distribution of MAO A and B in the normal human brain investigates the effects of disease and aging on MAO A and B analyzes a critical role for MAO in the toxic action in Parkinson's disease elucidates selegiline's novel ability to delay the progression or repair the damage of dopaminergic neurons discusses the usefulness of MAO inhibitors in psychiatric disease and more!

Autoren/Hrsg.

Lieberman

Fachgebiete

• Naturwissenschaften Biowissenschaften Enzymologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft

Inhaltsverzeichnis

The Distribution of Monoamine Oxidases A and B in Normal Human Brain, Karin N. WestlundEffects of Disease and Aging on Monoamine Oxidases A and B, Manfred Gerlach, Peter Riederer, and Moussa B. H. YoudimBiochemistry and Mechanism of Action of Monoamine Oxidases A and B, Eimear M. O'Brien and Keith F. TiptonThe Structure, Gene, and Promoter Organization of Monoamine Oxidases A and B, Jean Chen Shih, Kevin Chen, Joseph S. Grimsby, Qin-Shi Zhu, and Timothy K. GallaherMolecular Genetics and Inheritance of Human Monoamine Oxidases A and B, Xandra O. Breakefield, Zheng-Yi Chen, Elizabeth Tivol, Christo Shalish, and Ian W. CraigRole of Monoamine Oxidase Genetics in the Etiology of Parkinson's Disease, Janice H. Kurth and Matthias C. KurthMultiple Forms of Monoamine Oxidase and Iron: Their Relevance to the Pathology and Treatment of Parkinson's Disease, Moussa B. H. Youdim, Dorit Ben-Shachar, and Peter RiedererA Critical Role for Monoamine Oxidase in Toxin Action in Parkinson's Disease, Peter JennerEffects of Monoamine Oxidase B Inhibitors on Dopaminergic Function: Role of 2-Phenylethylamine and Aromatic L-Amino Acid Decarboxylase, Augusto V. Juorio, Xin-Min Li, I. A. Paterson, and Alan A. BoultonInhibition of Monoamine Oxidase B and the Neuroprotective Effects of Selegiline, Kevin T. FinneganReduction of Nerve Cell Death by Deprenyl Without Monoamine Oxidase Inhibition, William G. Tatton, Nadine A. Seniuk, William Y. H. Ju, and Karen S. AnsariMonoamine Oxidase Inhibitors as Neuroprotective Therapy, Warren Olanow and Donald B. CalneSelegiline as Symptomatic Treatment for Parkinson's Disease, Abraham LiebermanMonoamine Oxidase Inhibitors in Alzheimer's Disease, Jody Corey-Bloom and Leon J. ThalRole of Monoamine Oxidase Inhibitors in Psychiatry, David J. Houlihan and Samuel Gershon