Mechoulam Cannabinoids as Therapeutics
Buch, Englisch, Reihe: Milestones in Drug Therapy
268 Seiten, Gebunden, Book, Format (B × H): 175 mm x 245 mm, Gewicht: 644 g
2005,
268 Seiten, Gebunden, Book, Format (B × H): 175 mm x 245 mm, Gewicht: 644 g
Reihe: Milestones in Drug Therapy
ISBN: 978-3-7643-7055-8
Verlag: Springer
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The first chapter, on the use of Cannabis in India, can be viewed as an expression of thanks to the herbal practitioners, who for centuries passed on the medical traditions associated with the drug. The chapter on chemistry is a short summary of active plant, synthetic and endogenous cannabinoids being investigated today, many of which are mentioned later in the book. Cannabidiol is an unusual cannabinoid - it does not bind to the known receptors and yet exerts a variety of effects. Hence a chapter is devoted to it. Further chapters deal with the endocannabinoid system and the endocannabinoids in a variety of conditions and physiological systems. The concluding chapter describes the research done on Sativex®, a standardized plant extract, shortly to be introduced in Canada as a drug for multiple sclerosis.
The intended audience is drug researchers (medicinal chemists, pharmacologists, clinicians), neuroscientists, physiologists, and clinicians interested in the effect of the endocannabinoid system in various physiological systems.
Cannabis in India: ancient lore and modern medicine.- Cannabinoid chemistry: an overview.- Cannabidiol as a potential medicine.- Endocannabinoids and regulation of fertility.- Cannabinoids in neurodegeneration and neuroprotection.- Role of the endocannabinoid system in learning and memory.- Cannabinoids and anxiety.- Cannabinoid targets for pain therapeutics.- Potential use of cannabimimetics in the treatment of cancer.- Cannabinoids: effects on vomiting and nausea in animal models.- The skeleton: stone bones and stoned heads?.- Cannabinoids and drugs of abuse.- Cannabinoids in appetite and obesity.- The development of Sativex® - a natural cannabis-based medicine.
Research
The first chapter, on the use of Cannabis in India, can be viewed as an expression of thanks to the herbal practitioners, who for centuries passed on the medical traditions associated with the drug. The chapter on chemistry is a short summary of active plant, synthetic and endogenous cannabinoids being investigated today, many of which are mentioned later in the book. Cannabidiol is an unusual cannabinoid - it does not bind to the known receptors and yet exerts a variety of effects. Hence a chapter is devoted to it. Further chapters deal with the endocannabinoid system and the endocannabinoids in a variety of conditions and physiological systems. The concluding chapter describes the research done on Sativex®, a standardized plant extract, shortly to be introduced in Canada as a drug for multiple sclerosis.
The intended audience is drug researchers (medicinal chemists, pharmacologists, clinicians), neuroscientists, physiologists, and clinicians interested in the effect of the endocannabinoid system in various physiological systems.
Cannabis in India: ancient lore and modern medicine.- Cannabinoid chemistry: an overview.- Cannabidiol as a potential medicine.- Endocannabinoids and regulation of fertility.- Cannabinoids in neurodegeneration and neuroprotection.- Role of the endocannabinoid system in learning and memory.- Cannabinoids and anxiety.- Cannabinoid targets for pain therapeutics.- Potential use of cannabimimetics in the treatment of cancer.- Cannabinoids: effects on vomiting and nausea in animal models.- The skeleton: stone bones and stoned heads?.- Cannabinoids and drugs of abuse.- Cannabinoids in appetite and obesity.- The development of Sativex® - a natural cannabis-based medicine.
Research
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