Medin / Fowler | Experimental and Applied Immunotherapy | Buch |

Medin / Fowler Experimental and Applied Immunotherapy

2011, 442 Seiten, Kartoniert, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 700 g
ISBN: 978-1-62703-822-5
Verlag: Springer, Berlin

Medin / Fowler Experimental and Applied Immunotherapy

Immunotherapy is now recognized as an essential component of treatment for a wide
variety of cancers. It is an interdisciplinary field that is critically dependent upon an
improved understanding of a vast network of cross-regulatory cellular populations and
a diversity of molecular effectors; it is a leading example of translational medicine
with a favorable concept-to-clinical-trial timeframe of just a few years. There are many
established immunotherapies already in existence, but there are exciting new cancer immunotherapies just on the horizon, which are likely to be more potent, less toxic and more cost effective than many therapies currently in use.

Experimental and Applied Immunotherapy is a state-of-the-art text offering a roadmap
leading to the creation of these future cancer-fighting immunotherapies. It includes essays
by leading researchers that cover a wide variety of topics including T cell and non-T
cell therapy, monoclonal antibody therapy, dendritic cell-based cancer vaccines, mesenchymal
stromal cells, negative regulators in cancer immunology and immunotherapy,
non-cellular aspects of cancer immunotherapy, the combining of cancer vaccines with
conventional therapies, the combining of oncolytic viruses with cancer immunotherapy,
transplantation, and more. The field of immunotherapy holds great promise that will
soon come to fruition if creative investigators can bridge seemingly disparate disciplines,
such as T cell therapy, gene therapy, and transplantation therapy. This text is a vital tool in the building of that bridge.



Weitere Infos & Material

Foreword, by Carl H. June, M.D.IT Cell Therapy: State-of-the-ArtChapter 1: Extending the Use of Adoptive T Cell Immunotherapy for Infections and Cancer, by Ulrike Gerdemann and Malcolm K. BrennerIINon-T Cell Therapeutic ApproachesChapter 2: B Lymphocytes in Cancer Immunology, by David SpanerChapter 3: Monoclonal Antibody Therapy for Cancer, by Christoph RaderChapter 4: Natural Killer Cells for Cancer Immunotherapy, by Yoko Kosaka and Armand KeatingChapter 5: Dendritic Cell Based Cancer Vaccines: Practical Considerations, by Elizabeth Scheid, Michael Ricci, and Ronan FoleyChapter 6: Mesenchymal Stromal Cells: an Emerging Cell-based Pharmaceutical, by Moïra François and Jacques GalipeauIIIT Cell Therapeutic ApproachesChapter 7: Tumor-specific Mutations as Targets for Cancer Immunotherapy, by Brad H. Nelson, John R. WebbChapter 8: Counteracting Subversion of MHC Class II Antigen Presentation by Tumors, by Jacques Thibodeau, Marie-Claude Bourgeois-Daigneault, and Réjean LapointeChapter 9: Mechanisms and Implications of Immunodominance in CD8+ T-Cell Responses, by Claude PerreaultChapter 10: T Regulatory Cells and Cancer Immunotherapy, by Adele Y. Wang and Megan K. LevingsChapter 11: Negative Regulators in Cancer Immunology and Immunotherapy, by Wolfgang Zimmermann and Robert KammererChapter 12: Genetically Engineered Antigen Specificity in T Cells for Adoptive Immunotherapy, by Daniel J. Powell Jr. and Bruce L. LevineIVNon-Cellular Aspects of Cancer ImmunotherapyChapter 13: Cytokine Immunotherapy, by Megan Nelles, Vincenzo Salerno, Yixin Xu, and Christopher J. PaigeChapter 14: Transcriptional Modulation using Histone Deacetylase Inhibitors for Cancer Immunotherapy, by Takashi MurakamiChapter 15: Combining Cancer Vaccines with Conventional Therapies, by Natalie Grinshtein and Jonathan BramsonChapter 16: Combining Oncolytic Viruses with Cancer Immunotherapy, byKyle Stephenson, John Bell, and Brian LichtyChapter 17: Radiation Therapy and Cancer Treatment: From the Basics
to Combination Therapies that Ignite Immunity, by David A. Jaffray, and Jeffrey A. Medin Chapter 18: Assessing Immunotherapy through Cellular and Molecular Imaging, by John W. Barrett, Bryan Au, Ryan Buensuceso, Sonali de Chickera, Vasiliki Economopoulos, Paula Foster, and Gregory A. DekabanVTransplantationChapter 19: Converging Themes in Allogeneic and Autologous Transplantation, by Daniel Fowler


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