Microbiota-Gut-Brain Axis and CNS Disorders

Recent Progress and Perspectives
Erscheinungsjahr 2025
ISBN: 978-0-443-21680-0
Verlag: Elsevier Science

Buch, Englisch, 514 Seiten, Format (B × H): 191 mm x 234 mm, Gewicht: 1039 g

Microbiota-Gut-Brain Axis and CNS Disorders: Recent Progress and Perspectives on Human Disease summarizes the main findings on gut-brain axis in different types of CNS disorders, providing a complete overview of the field. The content helps unravel the complex interactions of the microbiota-gut-brain-axis in CNS disorders to pave a better understanding of microbiota-mediated pathogenesis, avenues for noninvasive prognosis, and therapeutic possibilities leveraging microbiota-gut-brain-axis modulations. Coverage includes the role of the microbiota-gut-brain axis and gut virome on human diseases including Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease, Depression and Anxiety, Autism Spectrum Disorder, Multiple Sclerosis, Stroke, and others.

This book will satisfy the urgent need for a broader view of the current associations between gut microbiota alterations and development of CNS disorders, including the use of novel therapeutic approaches for restoring the correct intestinal bacteria content. It is the perfect reference for translational and clinical gut and microbiome researchers tackling the challenges of delivering genes and drugs in a more targeted and efficient manner for the treatment of CNS disorders.

Autoren/Hrsg.

Mishra, Neeraj

Kumar, Anoop

Fachgebiete

• Interdisziplinäres Wissenschaften Wissenschaften: Forschung und Information Forschungsmethodik, Wissenschaftliche Ausstattung
• Naturwissenschaften Biowissenschaften Biowissenschaften
• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft

Inhaltsverzeichnis

1. Introduction: An overview of Microbiota-Gut- Brain Axis
2. Role of Microbiota-Gut- Brain Axis in Alzheimer disease and possible interventions
3. Role of Microbiota Gut- Brain axis in Parkinson’s disease
4. Role of Microbiota-Gut- Brain Axis in Huntington’s disease and possible interventions
5. Role of Microbiota-Gut- Brain Axis in depression and anxiety
6. Role of microbiome- Gut Brain axis in autism spectrum disorder (ASD)
7. Role of Microbiota- Gut brain axis in autoimmunity and Multiple Sclerosis
8. Role of Microbiome Gut- Brain axis in stress
9. Role of Microbiota- Gut Brain Axis in epilepsy and possible interventions
10. Role of Microbiota- Gut Brain Axis in migraine and possible interventions
11. Role of Microbiota- Gut Brain Axis in stroke and possible interventions
12. Role of Microbiota- Gut Brain Axis in brain infections and possible interventions
13. Role of Microbiome Gut- Brain axis in brain disorders
14. Role of GUT microbiota in neuropsychiatric and neurological disorders
15. Role of Microbiota- Gut Brain Axis in Obesity on Cognitive Functions and Mood
16. Role of Microbiota- Gut Brain Axis on Neurotransmitters modulation
17. Role of gut virome and mycobiome in neurological disorders
18. Role of nutraceuticals in neurological diseases
19. Future prospective of Microbiome- Gut brain axis for treatment of CNS disorders

Über Autor(innen)

Kumar, Anoop
Anoop Kumar is Assistant Professor in the Department of Pharmacology at the Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR), Delhi Pharmaceutical Sciences and Research University (DPSRU), Government of NCT of Delhi, India. He has held academic and research positions in pharmaceutical education, translational research, and the pharmaceutical industry. His professional activities include teaching, research, editorial service, ethics committee responsibilities, and engagement with professional organizations. His research interests include drug repurposing, meta-analysis of clinical trials, network pharmacology, pharmacoeconomics, pharmacovigilance, and experimental pharmacology. He has contributed to scientific publishing and research initiatives that support evidence-based approaches to drug discovery, development, and healthcare decision-making.

Mishra, Neeraj
Neeraj Mishra is Professor and Head of the Department of Pharmaceutics at the Amity Institute of Pharmacy, Amity University Madhya Pradesh, Gwalior, India. His academic work focuses on novel drug delivery systems, including localized, targeted, and controlled delivery approaches using nanocarrier and microparticle-based technologies. His research interests encompass therapies for cancer and neurodegenerative disorders, and he has extensive experience in teaching, research supervision, and scholarly publishing. He has also contributed to innovation in pharmaceutical sciences through intellectual property development and collaborative academic activities. Through his research and educational initiatives, he supports the advancement of drug delivery strategies and pharmaceutical research.