Buch, Englisch, 380 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 758 g
Buch, Englisch, 380 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 758 g
Reihe: Handbook of Experimental Pharmacology
ISBN: 978-3-540-73258-7
Verlag: Springer Berlin Heidelberg
This essential work, edited by two researchers at London’s famous Queen Mary’s medical school targets one of the most important areas in medical development today. These days, antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions. They are, indeed, becoming the molecules of choice for further combination therapies and cell engineering. In this timely work, a slew of expert in the field of drug development summarize all the current developments and clinical successes.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
- Naturwissenschaften Biowissenschaften Molekularbiologie
Weitere Infos & Material
Historical Development of Monoclonal Antibody Therapeutics.- Preclinical Safety Evaluation of Monoclonal Antibodies.- Molecular Developments in Antibody Production.- Engineering Antibodies for Stability and Efficient Folding.- Human Monoclonal Antibodies from Transgenic Mice.- Antibodies to Cytokines.- Anti-TNF Antibodies: Lessons from the Past, Roadmap for the Future.- Therapeutic Anti-VEGF Antibodies.- Humanized Antihuman IL-6 Receptor Antibody, Tocilizumab.- Antibodies to Cell Markers.- Anti-CD20Monoclonal Antibody in Rheumatoid Arthritis and Systemic Lupus Erythematosus.- Herceptin.- The Use of CD3-Specific Antibodies in Autoimmune Diabetes: A Step Toward the Induction of Immune Tolerance in the Clinic.- Monoclonal Antibody Therapy for Prostate Cancer.- Anti-IgE and Other Antibody Targets in Asthma.- Development of Antibody-Based Cellular and Molecular Therapies.- Cytokine, Chemokine, and Co-Stimulatory Fusion Proteins for the Immunotherapy of Solid Tumors.- The T-Body Approach: Redirecting T Cells with Antibody Specificity.- Intracellular Antibodies (Intrabodies) and Their Therapeutic Potential.
