Buch, Englisch, 1268 Seiten, Format (B × H): 215 mm x 303 mm, Gewicht: 3929 g
Buch, Englisch, 1268 Seiten, Format (B × H): 215 mm x 303 mm, Gewicht: 3929 g
ISBN: 978-1-58829-202-5
Verlag: Humana Press
Review From the First Edition
"The selection of topics, the ability of the contributors to present complex topics in a clear, concise manner, and the format should all contribute to making this book the standard text and reference in its field. It should be in the collection of every medical library and on the bookshelf of every physician interested in keeping up with the transformation of medicine by molecular genetics." 5 Stars-Doody's Health Science Book Review Journal.
The second edition of Principles of Molecular Medicine features new discoveries that have occurred in molecular medicine along with rapid technologic advances that have revolutionized the diagnosis and treatment of diseases. As in the first edition, this book includes chapters describing advances in fields paralleling traditional medical texts, and will be especially useful to specialistswho are updating their education, practicing physicians interested in keeping abreast of new developments and students appropriately curious about what is known and what lies ahead. In addition, new developments in understanding biology of previously untreatable neurodegenerative diseases are included in this edition.
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Weitere Infos & Material
Genetics.- Mendelian Inheritance.- Nontraditional Inheritance.- Identifying Causal Genetic Factors.- Cancer Genetics and Molecular Oncology.- Pharmacogenetics.- Hemophilia as a Model Disease for Gene Therapy of Genetic Disorders.- Genetic Counseling.- Animal Models in Biomedical Research.- Ethical, Legal, and Social Implications.- Cardiology.- Congenital Heart Disease.- Inherited Cardiomyopathies.- Heart Failure.- Aortic Diseases.- Atherosclerotic Coronary Disease.- Lipid Metabolism and Coronary Artery Disease.- Hypertension.- Cardiac Hypertrophy.- Arrhythmias.- Genomics.- Cardiovascular Gene Therapy.- Pulmonary Diseases.- Idiopathic Interstitial Pneumonias.- Asthma.- Pulmonary Emphysema.- Pulmonary Hypertension.- Acute Lung Injury.- Primary Ciliary Dyskinesia.- Cystic Fibrosis.- Gene Therapy for Lung Diseases.- Sarcoidosis.- Disorders of Pulmonary Surfactant Homeostasis.- Endocrinology.- Mechanisms of Hormone Action.- Diabetes Mellitus.- Pituitary Function and Neoplasia.- Growth Hormone Deficiency Disorders.- Thyroid Disorders.- Disorders of the Parathyroid Gland.- Congenital Adrenal Hyperplasia.- Adrenal Diseases.- Multiple Endocrine Neoplasia Type 1.- Multiple Endocrine Neoplasia Type 2.- Disorders of Sex Determination and Differentiation.- Sex Chromosome Disorders.- Disorders of Pubertal Development.- Defects of Androgen Action.- Molecular Endocrinology of the Testis.- Ovarian Diseases.- Metabolic Disorders.- Gastrointestinal Regulation of Food Intake.- Cellular Regulation of Lipolysis.- Fat-Induced Insulin Resistance and Atherosclerosis.- Metabolic and Molecular Aspects of Sarcopenia.- Adipose Tissue Development and Metabolism.- Gastroenterology.- Hepatitis C.- Molecular Diagnostics in Hepatitis B.- Hereditary Hemochromatosis.- Pancreatic Exocrine Dysfunction.- Small and Large Bowel Dysfunction.- The Molecular Mechanisms of Helicobacter pylori-Associated Gastroduodenal Disease.- Nephrology.- Nitric Oxide Synthase and Cyclooxygenase in the Kidneys.- Hypertensionand Sodium Channel Turnover.- Nephrogenic Diabetes Insipidus st[Water and Urea Transport.- Glomerulonephritis and Smad Signaling.- Interstitial Nephritis.- The Pathophysiology of Acute Renal Failure.- Loss of Lean Body Mass in Uremia.- Mechanisms of Renal Allograft Rejection.- Musculoskeletal.- Muscle Development and Differentiation.- Skeletal Muscle Structure and Function.- Stem Cells and Muscle Regeneration.- Skeletal Muscle Hypertrophy and Response to Training.- Muscular Dystrophies.- Rhabdomyosarcomas.- Oncology.- Apoptosis.- Colorectal Cancer.- Breast Cancer.- Lung Cancer.- Discoveries and Frontiers in Prostate Cancer Translational Sciences.- Cutaneous Melanoma.- Applications of Gene Expression Profiling to the Study of Malignant Gliomas.- Acute Myeloid Leukemias.- Acute Lymphoblastic Leukemia.- Chronic Myelogenous Leukemia.- Non-Hodgkin’s Lymphoma and Chronic Lymphocytic Leukemia.- Multiple Myeloma.- HIV-1, AIDS, and Related Malignancies.- Hematology.- Disorders of the Red CellMembrane.- Paroxysmal Nocturnal Hemoglobinuria.- Iron Metabolism.- Correction of Genetic Blood Defects by Gene Transfer.- Bone Marrow Failure Syndromes.- Coagulation Disorders.- Advances in Transfusion Safety.- Immunology And Infectious Diseases.- Immunomodulation.- HIV Molecular Biology, Treatment Resistance.- Cellular and Molecular Aspects of Pneumonia.- Molecular Pathogenesis of Fungal Infections.- Dermatology.- Psoriasis.- Atopic Dermatitis.- Pemphigus Foliaceus, Pemphigus Vulgaris, Paraneoplastic Pemphigus, Bullous Pemphigoid, Herpes Gestationis, and Cicatricial Pemphigoid.- Systemic Lupus Erythematosus.- Systemic Sclerosis.- Diseases With Signaling and Transcriptional Abnormalities.- Genetic Skin Diseases With Neoplasia.- Melanoma and Nevi.- Disorders of Hypopigmentation.- Epidermolysis Bullosa.- Connective Tissue Disorders.- Genetic Epidermal Diseases.- Genetic Hair and Nail Defects.- Metabolic Genetic DisordersWith Prominent Skin Findings.- Heritable Conditions Affecting Tissues of the Oral Cavity.- Neurology.- The Genetic Basis of Human Cerebral Cortical Malformations.- Muscular Dystrophies.- Channelopathies of the Nervous System.- Charcot-Marie-Tooth Disease and Related Peripheral Neuropathies.- Amyotrophic Lateral Sclerosis and Related Motor Neuron Disorders.- Trinucleotide Repeat Disorders.- Parkinson’s Disease.- Genetics and Neurobiology of Alzheimer’s Disease and Frontotemporal Dementias.- Prion Diseases.- Narcolepsy and Other Neurological Sleep Disorders.- Neurofibromatosis 1 and 2.- Axonal Regeneration and Recovery From Chronic Central Nervous System Injury.- Psychiatry.- Molecular Mechanisms Regulating Behavior.- The Complex Genetics of Psychiatric Disorders.- Treating Depression.- Anxiety Disorders.- Trauma Spectrum Disorders.- Schizophrenia.- Disorders of Substance Abuse and Dependence.- Autism and Related Disorders.
