Receptor Endocytosis and Signalling in Health and Disease - Part B

Erscheinungsjahr 2023
ISBN: 978-0-323-95559-1
Verlag: William Andrew Publishing

Buch, Englisch, 300 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

Receptor Endocytosis and Signalling in Health and Disease, Part B, Volume 196 highlights the different aspects of receptor endocytosis and signaling, covering several receptors which are associated with different organs and that play a key role in normal functioning in the body, including somatostatin, Mas receptor, AMPA, Dopamine, 5-HT1-2, GABA, GPCR, nuclear receptor, Integrin, BCR, CRHR1, etc. Chapters in this new release include Internalization of somatostatin receptors in brain and periphery, Mas receptor, signaling and trafficking in health and disease, Endocytosis of AMPA receptors: Role in neurological conditions, Endocytosis of dopamine receptor: Signaling in brain, and more.

Additional chapters cover Endocytosis of LXRs: Signalling in liver, Endocytosis of LDL receptor: Importance in cardiovascular diseases, Advances in the molecular level understanding of G-protein-coupled receptor, Nuclear receptor: Structure and function, Integrin receptor trafficking in health and disease, B Cell Receptor (BCR) endocytosis,CRHR1 endocytosis: Spatiotemporal regulation of receptor signaling, and much more.

Zielgruppe

<p>This volume will be an excellent basis from which scientific knowledge can grow, widen, and accelerate receptor biology towards biomedical applications. This volume will be useful to undergraduate and postgraduate students, postdoctoral fellow, faculty, and scientists.</p>

Autoren/Hrsg.

Weitere Mitwirkende

Mani, Indra

Singh, Vijai

Fachgebiete

• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

Preface

Indra Mani and Vijai Singh

- Advances in the molecular level understanding of G-protein coupled receptor

Adhiraj Roy

2. Prion receptors, prion internalization, intra- and inter-cellular transport

Luigi Celauro, Marco Zattoni and Giuseppe Legname

3. Internalization of somatostatin receptors in brain and periphery

Zsolt Csaba and Pascal Dournaud

4. Endocytosis of AMPA receptors: Role in neurological conditions

Norbert Bencsik, Carlos Omar Oueslati Morales, Angelika Hausser and Katalin Schlett

5. Endocytosis of dopamine receptor: Signaling in brain

Ichiro Kawahata and Kohji Fukunaga

6. Endocytosis and signaling of 5-HT1A receptor

Ragini, Sakshi, Ashok Saini and Indra Mani

7. Endocytosis of GABA receptor: Signaling in nervous system

Preeti Sharma, B. Sharan Sharma, Hardik Raval and Vijai Singh

8. The endocytosis, trafficking, sorting and signaling of neurotrophic receptors

Katja Burk

9. Endocytosis of glutamate receptor: Signaling in neurological conditions

Prerna Yadav, Mansi Podia, Shashi Prabha Kumari and Indra Mani

10. Nuclear receptor: Structure and function

Pranati Sar

11. CRHR1 endocytosis: Spatiotemporal regulation of receptor signaling

Paula A. dos Santos Claro, Micaela Silbermins, Carolina Inda and Susana Silberstein

12. Amyloid precursor protein in Alzheimer's disease

Rupesh Maurya, Gargi Bhattacharjee, Khushal Khambhati, Nisarg Gohil, Priyanka Singh, Indra Mani, Dinh-Toi Chu, Suresh Ramakrishna, Pau Loke Show and Vijai Singh

13. Integrin receptor trafficking in health and disease

Victor Samuel, Thejaswitha Rajeev, Lariza Ramesh and Ananthalakshmy Sundararaman

14. Synthetic receptors in medicine

Sarita Mishra, Mahima Raval, Vijai Singh and Anand K. Tiwari

15. Receptor biology: Challenges and opportunities

Indra Mani and Vijai Singh

Über Autor(innen)

Mani, Indra
Dr. Indra Mani is an Assistant Professor in the Department of Microbiology, Gargi College, University of Delhi (DU), New Delhi, India. He received M.Sc. in Microbiology from Bundelkhand University (BU), Jhansi, UP, India and Ph.D. in Biochemistry from Banaras Hindu University (BHU), Varanasi, UP, India. He completed postdoctoral training in the Department of Physiology, School of Medicine, Tulane University, New Orleans, USA. He has also worked as a Senior Research Officer (SRO) in the Department of Medicine, All India Institute of Medical Sciences (AIIMS), New Delhi, India. He has more than 10 years of research and teaching experience in Microbiology, Molecular Genetics, Cell Signaling, and Bioinformatics. He has published 49 articles in peer reviewed journals and 22 book chapters. He has presented several papers in the different national and international conferences. He has extensive experience in fluorescence/confocal microscopy, receptor internalization, trafficking and signaling, molecular cytogenetics, microbial characterization, and in silico analysis. He serves as a reviewer of peer-reviewed journals and also a member of national and international societies.

Singh, Vijai
Prof. Vijai Singh is currently serving as Head of the Department of Biosciences, School of Science and Dean (Research & Innovation) at Indrashil University, Rajpur, Mehsana, India. Prior to this, he held the position of Associate Professor in the same department at Indrashil University. He has also served as Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, and in the Department of Biotechnology at the Invertis University, Bareilly, India. Earlier of his career, Prof. Singh worked as a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and at the School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He earned his Ph.D. in Biotechnology in 2009 from the ICAR-National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India. His doctoral research focused on the development of molecular and immunoassays for the diagnosis of Aeromonas hydrophila. Prof. Singh's research interests lies in the design and construction of novel biosynthetic pathways for production of medically and industrially important biomolecules. His laboratory is also actively engaged in developing CRISPR-Cas systems for gene knock out, knock in, gene regulation and diagnostic. With over 15 years of research and teaching experience, his areas of expertise include synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has an extensive academic record, with over 110 articles, 89 book chapters, 26 books and 3 patents to his credits. Prof. Singh has received number of prestigious awards, including the Bioclues Innovation, Research and Development Award (2023) from the BIOCLUES Society, the Vice Chancellor's Best Research Award (2023) from Indrashil University, and the Agathiyar Chemical Biology Award (2023) from the Society of Chemical and Synthetic Biology. At Indrashil University, he currently serves as chairman of the Board of Study, and is a member of the Academic Council of Indrashil University. He also holds the position of the Member Secretary of the Institutional Biosafety Committee (IBSC) at the university. Dr. Singh is actively involved in national and international scientific advisory roles.