Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part B

Erscheinungsjahr 2021
ISBN: 978-0-323-85297-5
Verlag: William Andrew Publishing

Buch, Englisch, 198 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

Reprogramming the Genome: Applications of CRISPR-Cas in Non-mammalian Systems Part B, represents the collation of chapters written by eminent scientists worldwide. CRISPR-Cas9 system is an RNA-mediated immune system of bacteria and archaea that protects from bacteriophage infections. It is one of the revolutionized technologies to uplift biology to the next stages. It is a simple, rapid, precise, and cost-effective tool for genome editing and regulation of a wide range of organisms. It has gained scientific and public attention worldwide. This volume mainly covers insect cell line, protozoans, zebrafish, drosophila, CRISPRi, patents as well as technology transfer, and many more. This book is a key source of information available in a single volume. This book will be useful for not only beginners in genome engineering, but also students, researchers, scientists, policymakers, and stakeholders interested in harnessing the potential of reprogramming of the genomes in several areas.

Zielgruppe

<p>This book will be valuable sources of information for not only beginner in area of genome engineering area, but also researchers, students, scientists, clinicians, stakeholders, policy makers and practitioners and many more. </p>

Autoren/Hrsg.

Weitere Mitwirkende

Singh, Vijai

Fachgebiete

• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

1. Development of insect cell line using CRISPR technology Ekene Emmanuel Nweke and Deepak B. Thimiri Govinda Raj

2. CRISPRing protozoan parasites to better understand the biology of diseases Apurva Kirti, Manish Sharma, Komal Rani and Abhisheka Bansal

3. CRISPR based genome editing of zebrafish Preeti Sharma, B. Sharan Sharma and Ramtej J. Verma

4. Using CRISPR-Cas9 based genome engineering tools in Drosophila melanogaster Deepti Trivedi

5. CRISPR interference and its applications Seyedkhashayar Ghavami and Amir Pandi

6. CRISPR-Cas systems: Challenges and future prospects Nisarg Gohil, Gargi Bhattacharjee, Navya Lavina Lam, Samuel D. Perli and Vijai Singh

7. Patents and technology transfer in CRISPR technology Lichelle Grobler, Essa Suleman and Deepak B. Thimiri Govinda Raj

Über Autor(innen)

Singh, Vijai
Prof. Vijai Singh is currently serving as Head of the Department of Biosciences, School of Science and Dean (Research & Innovation) at Indrashil University, Rajpur, Mehsana, India. Prior to this, he held the position of Associate Professor in the same department at Indrashil University. He has also served as Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, and in the Department of Biotechnology at the Invertis University, Bareilly, India. Earlier of his career, Prof. Singh worked as a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and at the School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He earned his Ph.D. in Biotechnology in 2009 from the ICAR-National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India. His doctoral research focused on the development of molecular and immunoassays for the diagnosis of Aeromonas hydrophila. Prof. Singh's research interests lies in the design and construction of novel biosynthetic pathways for production of medically and industrially important biomolecules. His laboratory is also actively engaged in developing CRISPR-Cas systems for gene knock out, knock in, gene regulation and diagnostic. With over 15 years of research and teaching experience, his areas of expertise include synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has an extensive academic record, with over 110 articles, 89 book chapters, 26 books and 3 patents to his credits. Prof. Singh has received number of prestigious awards, including the Bioclues Innovation, Research and Development Award (2023) from the BIOCLUES Society, the Vice Chancellor's Best Research Award (2023) from Indrashil University, and the Agathiyar Chemical Biology Award (2023) from the Society of Chemical and Synthetic Biology. At Indrashil University, he currently serves as chairman of the Board of Study, and is a member of the Academic Council of Indrashil University. He also holds the position of the Member Secretary of the Institutional Biosafety Committee (IBSC) at the university. Dr. Singh is actively involved in national and international scientific advisory roles.