A History of Angiogenesis

Discoveries, Research and the Therapeutic Potential
Erscheinungsjahr 2025
ISBN: 978-0-443-13979-6
Verlag: Elsevier Science Publishing Co Inc

Buch, Englisch, 180 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

A History of Angiogenesis: Discoveries, Research and the Therapeutic Potential presents a recent history of discoveries in the angiogenic field that contribute to the development of the anatomical knowledge of the process, experimental models, and new pharmacological approaches in different angiogenesis-related diseases. This multifaceted book is enriched with deep scientific contents, and each chapter clearly defines historical steps, the emerging role during the years of new morphological findings, molecular pathways, and targets. Focus is also directed on key challenges associated and future directions. The history of angiogenesis research is an intriguing tool for discovering answers to a wide array of queries arising in the biological and medical world. This comprehensive resource skillfully integrates all the key aspects related to angiogenesis, and will be of immense help to students, researchers, and industry experts who want to explore the last two decades of angiogenesis discoveries and research.

Autoren/Hrsg.

Ribatti, Domenico

Bocci, Guido

Natale, Gianfranco

Fachgebiete

• Wirtschaftswissenschaften Betriebswirtschaft Unternehmensforschung
• Naturwissenschaften Biowissenschaften Biowissenschaften
• Mathematik | Informatik EDV | Informatik Business Application Unternehmenssoftware

Inhaltsverzeichnis

1. Introduction 2. Angiogenesis before 2000 - Cardiovascular system and angiogenesis during the centuries 3. Vasculogenesis, angiogenesis, and new types of vascular growth 4. In vitro and in vivo assays 5. New frontiers in angiogenesis research 6. New Frontiers of Lymphangiogenesis 7. Early work on the development of inhibitors of angiogenesis as anti-tumor agents 8. Approved anti- and pro-angiogenic drugs in the two last decades: A historical landscape of the therapeutic opportunities 9. Metronomic chemotherapy: more than twenty years of preclinical and clinical evidence

Über Autor(innen)

Bocci, Guido
Guido Bocci, MD PhD, is currently a Full Professor of Pharmacology at the University of Pisa. He is an European Certified Pharmacologist (EuCP). He maintains relevant international collaborations with various groups in Europe and North America. His international experience is closely related to the 3-year post-doctoral fellowship at the University of Toronto in the Kerbel's Laboratory, with whom he continued to work in the following decades on numerous projects. He has been a PI of various projects granted by AIRC, ITT and foundations. He is in the editorial board of various journals, associate editor of Frontiers in Oncology, Frontiers in Pharmacology and regional editor of Clinical Cancer Drugs. He has been a grant reviewer for UK association for Cancer Research, South Plains Foundation (USA), French National Cancer Institute (France), Genesis Oncology Trust (New Zealand), Innsbruck Medical University (Austria), United States-Israel Binational Science Foundation and The German Israeli Foundation. Prof. Bocci is author of 4 national and 3 international patents, he has published 174 articles on international journals, 18 chapters on international and national books, and 1 international book as an editor on metronomic chemotherapy. The main research activity of Prof. Bocci has been focused on antineoplastic chemotherapy and antiangiogenic research, including both in vitro and in vivo experimental settings, and clinical pharmacology of chemotherapeutic drugs and antiangiogenic therapies. He has been deeply involved in the birth and development of metronomic chemotherapy concept in both pre-clinical and clinical trials.

Ribatti, Domenico
Domenico Ribatti was awarded his M.D. degree in October 1981, with full marks. In 1983, D.R. joined the Medical School as Assistant at the Institute of Human Anatomy, University of Bari. In 1984, he took the specialization in Allergology. In 1989, he spent one year in Geneva, working at the Department of Morphology (Prof. R. Montesano). In 2008, he received the honoris causa degree in Medicine and Pharmacy form the University of Timisoara (Romania). D.R. is author of 866 publications as reported in PUBmed and contributed to 50 chapters to books. Overall, his papers have been cited 51153 times.

He has published many books with both Elsevier and Springe