Buch, Englisch, Band 0, 182 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 576 g
Reihe: Current Clinical Pathology
Buch, Englisch, Band 0, 182 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 576 g
Reihe: Current Clinical Pathology
ISBN: 978-1-61779-357-8
Verlag: Humana Press
Gene expression studies have revealed diagnostic profiles and upregulation of specific pathways in many solid tumors. The explosion of new information in gene expression profiling could potentially lead to the development of tailored treatments in many solid tumors. In addition many studies are ongoing to validate these signatures also in predicting response to hormonal, chemotherapeutic and targeted agents in breast cancer as well as in other tumors.
Diagnostic, Prognostic and Therapeutic Value of Gene Signatures provides readers a useful and comprehensive resource about the range of applications of microarray technology in oncological diseases. Topics covered include gene signatures and soft tissue sarcomas, prognostic relevance of breast cancer signatures, gene expression profiling of colorectal cancer and liver metastasis, gene signatures in GISTs, CNVs and gene expression profiles in pancreatic cancer, and gene signatures in head/neck, lung and gastric tumors.
Diagnostic, Prognostic and Therapeutic Value of Gene Signatures will be of great value to residents and fellows, physicians, pathologists and medical oncologists.
Zielgruppe
Professional/practitioner
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pathologie, Cytopathologie, Histopathologie
Weitere Infos & Material
Preface
Chapter 1 Gene signatures and soft tissue sarcomas: status of art and perspectives
Bruno Vincenzi, Anna Maria Frezza, Daniele Santini, and Giuseppe Tonini
Chapter 2 Heterogeneity of breast cancer: gene signatures and beyond
Gaia Schiavon, Marcel Smid, Gaorav P. Gupta, Stefania Redana, Daniele Santini, and John W.M. Martens
Chapter 3 Gene signatures in CRC and liver metastasis
Daniele Fanale, Lidia Corsini, Sergio Rizzo, and Antonio Russo
Chapter 4 Gene signatures in Gastrointestinal Stomal Tumors (GIST)
Piotr Rutkowski, Giuseppe Badalamenti, Laura La Paglia, Joanna Przybyl, and Maria Debiec-Rychter
Chapter 5 Pancreatic Cancer Genetics
Juan Iovanna, Ezequiel Luis Calvo, Jean Charles Dagorn, and Nelson Dusetti
Chapter 6 Diagnostic, prognostic and therapeutic value of gene signatures in non-small-cell lung cancer
Rafael Rosell, Miquel Taron, Christian Diego Rolfo, Delvys Rodriguez-Abreu, and Jia Wei
Chapter 7 Gene signatures in Gastric Cancer
Laura Ottini, Mario Falchetti, and Gabriella Nesi
Chapter 8 Gene signatures in Colorectal Cancer
Alessandro Lugli and Inti Zlobec
Chapter 9 The role of epigenetics in cancer: from molecular function to high-throughput assays
Aleksandra Pekowska, Joaquin Zacarias-Cabeza, Jinsong Jia, Pierre Ferrier, and Salvatore Spicuglia
Chapter 10 Primary Epithelial Ovarian Neoplasms: New concepts concerning origin, pathogenesis and classification based on morphology, immunomarkers, molecular features and gene expression studies
Bernard Czernobilsky, Leonor Leider-Trejo, and Antonio Russo
Chapter 11 Thyroid carcinoma: molecular signature by histotype specific mutations and gene expression patterns
Umberto Malapelle, Claudio Bellevicine, Lajos Pustzai, and Giancarlo Troncone
