Genetic Polymorphism and cancer susceptibility

1. Auflage 2021
ISBN: 978-981-336-701-2
Verlag: Springer Nature Singapore

Buch, Englisch, 339 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 552 g

This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field.

Zielgruppe

Research

Autoren/Hrsg.

Sameer, Aga Syed

Nissar, Saniya

Banday, Mujeeb Zafar

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik

Inhaltsverzeichnis

Chapter 1. Polymorphisms and Mutation: What is difference?.- Chapter 2. Single nucleotide polymorphisms and pharmacogenomics.- Chapter 3. Impact of MicroRNA Polymorphisms on Breast Cancer Susceptibility.- Chapter 4. From inflammation to cancer: Role of genetic polymorphisms of Inflammatory Pathway Molecules in Gastric Cancer.- Chapter 5. Colorectal Cancer and genetic polymorphism in key regulatory low penetrance genes.- Chapter 6. Role of Genetic Polymorphisms in Breast Cancer.- Chapter 7. Genetic Polymorphisms of Essential Immune Pathogenic Response Genes and Risk of Cervical Cancer.- Chapter 8. Thyroid Cancer and genetic polymorphism.- Chapter 9. SNPs of TLRs and Bladder Cancer.- Chapter 10. Role of genetic polymorphisms in Lung Cancer.

Über Autor(innen)

Dr. Syed Sameer Aga is currently working as an Assistant Professor of Biochemistry in the Department of Basic Medical Sciences, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia. He is also serving as the Chairman of the Quality Unit in College of Medicine, KSAU-HS. Dr. Syed is a life-time member of many societies related to genetics, molecular biology and medical education like the Association of Clinical Biochemists of India, Society of Indian Academy of Medical Genetics, Middle East Molecular Biology Sources, Asian Council of Science Editors, and Saudi Society of Medical Education, etc. He is also serving as the Associate Editor in three Journals, Frontiers in Oncology – Molecular Biosciences section, BioMed Research International, World Journal of Biological Chemistry and Current Drug Metabolism. He also serves as a full time reviewer for various journals including European Journal of Cancer Prevention (Lippincott Williams & Wilkins), PLOS One & PLOS Genetics (Public Library of Science), World Journal of Gastroenterology (Baishideng Publishing), Gene & Meta Gene (Elsevier Publishing), Bioscience Reports (Portland Press), Journal of Clinical Laboratory Analysis (John Wiley & Sons) and Tumor Biology (Sage Journals) etc. His research interests are focused on cancer biology and he has published more than seventy-five research and review articles in high repute journals with an h-index of 20 and authored ten books.

Dr. Mujeeb Zafar Banday is presently working as a Senior Researcher and Lecturer in the Department of Biochemistry, Govt. Medical College, Srinagar. Dr. Banday has completed his Ph.D., M.Phil. and M.Sc. in Biochemistry from the University of Kashmir, J&K, India. He is serving as the review editor and associate reviewer  for the journal, Frontiers in Oncology - Cancer Epidemiology and Prevention (Frontiers Group) and full time reviewer for various journals includingGene (Elsevier Publishing), Bioscience Reports (Portland Press), BioMed Research International (Hindawi Publishing) and Toxicology and Environmental Health Sciences Review (Springer Nature). He has authored more than twenty research and review articles and three books.

Dr. Saniya Nissar is presently working as a Senior Researcher and Lecturer in the Department of Biochemistry, Govt. Medical College, Srinagar. She has completed her PhD, MPhil, and MSc in clinical biochemistry from the University of Kashmir, J&K, India. She works as free-lancescientific content writer with many scientific magazines. She has published more than thirty research and review articles and authored four books.