Sauer / Shah / Laurindo | Studies on Cardiovascular Disorders | Buch |

Sauer / Shah / Laurindo Studies on Cardiovascular Disorders

1. Auflage 2010, 590 Seiten, Gebunden, Book, Format (B × H): 155 mm x 235 mm, Gewicht: 1039 g Reihe: Oxidative Stress in Applied Basic Research and Clinical Practice
ISBN: 978-1-60761-599-6
Verlag: Springer, Berlin

Sauer / Shah / Laurindo Studies on Cardiovascular Disorders

The role of reactive oxygen species (ROS) in the cardiovascular system is Jan- faced. Whereas low concentrations of ROS are involved in variety of physiological signalling events, oxidative stress resulting from deregulated overproduction of ROS and/or impaired antioxidant defences contributes to cardiovascular disease. The actions of ROS in the cardiovascular system are a fascinating topic, not only for the basic science researcher but also for the clinician who is interested in seeking new therapies for his patients suffering from cardiovascular disease. The current book provides a comprehensive overview of the molecular mechanisms and pathoph- iological settings in which chronic and detrimental oxidative stress arises within the heart and vasculature. The book also considers currently discussed strategies in avoiding chronic redox stress resulting from exposure to risk factors or various cardiovascular interventions. The series starts with an overview by Denise de Castro Fernandes, Diego Bonatto and Francisco Laurindo of redox signaling models that could underlie the dev- opment of redox-associated cardiovascular disorders. The interactions of proteins within signalling cascades with ROS and the regulation of such interactions by the anti-oxidative capacity of the cell are discussed. Rebecca Charles, Joseph Burgoyne and Philip Eaton report on redox-mediated modi cations of proteins under ph- iological and pathophysiological conditions and the variety of post-translational oxidative modi cations that explain redox sensing and signal transduction by proteins at the molecular level. ROS are generated during embryogenesis and may be involved in the proper development of the cardiovascular system.



Weitere Infos & Material

PrefaceContributor's ListChapters:1) The evolving concept of oxidative stressDenise de Castro Fernandes, Diego Bonatto, Francisco R. M. Laurindo2) Mechanisms of redox signaling in cardiovascular diseaseRebecca L. Charles, Joseph R. Burgoyne and Philip Eaton3) Reactive oxygen and nitrogen species in cardiovascular differentiation of stem cellsHeinrich Sauer and Maria Wartenberg
4) Reactive Oxygen Species (ROS) and the sensory neurovascular componentRabea Graepel BSc, Jennifer Victoria Bodkin BSc, MRes, & Susan Diana Brain BSc, PhD5) Mitochondrial Reactive Oxygen Species in Myocardial Pre- and Post-ConditioningAriel R. Cardoso, Bruno B. Queliconi* and Alicia J. Kowaltowski6) Coenzyme Q9/Q10 and Healthy HeartSamarjit Das, Somak Das and Dipak K. Das7) Oxidative and proteolytic stress in homocysteine associated cardiovascular diseasesKarni S. Moshal, Munish Kumar, Neetu Tyagi, Paras Kumar Mishra, Saumi Kundu, Suresh C. Tyagi8) Functional studies of NADPH oxidases in human vasculatureTomasz J Guzik9) Relationship of the CYBA gene polymorphisms with oxidative stress and cardiovascular riskGuillermo Zalba, PhD and Javier Díez, MD, PhD10) Redox-related genetic markers of cardiovascular diseasesChristian Delles, MD, and Anna F. Dominiczak, MD11) NADPH oxidases and blood-brain barrier dysfunction in strokeTimo Kahles, MD, Sabine Heumüller and Ralf P. Brandes, MD12) Smoking-Induced Oxidative Stress in the Pathogenesis of Cardiovascular DiseasesDavid Bernhard PhD13) Oxidative Stress in Vascular AgingAnna Csiszar, MD, PhD and Zoltan Ungvari, MD, PhD14) Oxidative Stress and Cardiovascular Disease in Diabetes MellitusDivya Gupta, Kathy K. Griendling and W. Robert Taylor15) Reactive Oxygen Species, Oxidative Stress and HypertensionRhian M Touyz MD, PhD, Andreia Chignalia, MSc, Mona Sedeek PhD16) Peripartum cardiomyopathy: Role of STAT-3 and reactive oxygen speciesDenise Hilfiker-Kleiner, PhD, Arash Haghikia, MD, andAndres Hilfiker, PhD17) Oxidative stress and inflammation after coronary angiographyRaymond Farah MD18) Oxidative Stress in Cardiac TransplantationGalen M. Pieper, Ph.D. and Ashwani K. Khanna, Ph.D19) Oxidative Stress and Atrial FibrillationAli A. Sovari and Samuel C. Dudley, Jr.20) Oxidative stress and the anti-oxidative capacity in myocardial infarctionYao Sun, MD, Ph.D.21) Oxidative Stress and Redox Signalling in Cardiac RemodellingMin Zhang MD, PhD, Alex Sirker MRCP and Ajay M Shah MD, FmedSci22) Oxidative Stress and Cardiovascular FibrosisSubramanian Pennathur, Louise Hecker, and Victor J. Thannickal23) Oxidative Risk Factors for Cardiovascular Disease in WomenM. Gago-Dominguez, Xuejuan Jiang, J. Esteban Castelao24) Protective effects of food on cardiovascular diseasesAlfonso Giovane, Biol.D., Ph.D., and Claudio Napoli, M.D., Ph.D., MBEth.25) Novel Synthetic Antioxidants and Nitrated Lipids: From Physiology to Therapeutic ImplicationsGloria V. López , PhD and Homero Rubbo, PhD26) Thioredoxin in the cardiovascular system - towards a thioredoxin-based anti-oxidative therapyBradford C. Berk27) The protective effect of melatonin on the heartAmanda Lochner28) Exercise Induced cardioprotection: Overview with an emphasis on the role of anti-oxidantsKaryn L. Hamilton and John C. Quindry29) Antioxidative properties of statins in the heartOliver Adam MD, Ulrich Laufs MD


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