Schizophrenia is the most widely known and feared mental illness worldwide, yet a rapidly growing literature from a broad spectrum of basic and clinical disciplines, especially epidemiology and molecular genetics, suggests that schizophrenia is the same condition as a psychotic bipolar disorder and does not exist as a separate disease. The goal is to document and interpret these data to justify eliminating the diagnosis of schizophrenia from the nomenclature. The author reviews the changing diagnostic concepts of schizophrenia and bipolar disorder with a historical perspective to clarify how the current conflict over explanations for psychosis has arisen. That two disorders, schizophrenia and bipolar, known as the Kraepelinian dichotomy, account for the functional psychoses has been a cornerstone of Psychiatry for over 100 years, but is questioned because of substantial similarities and overlap between these two disorders. Literature in the field demonstrates that psychotic patients are frequently misdiagnosed as suffering from the disease called schizophrenia when they suffer from a psychotic mood disorder. Such patients, their families, and their caretakers suffer significant disadvantages from the misdiagnosis. Psychotic patients misdiagnosed with schizophrenia receive substandard care regarding their medications, thus allowing their bipolar conditions to worsen. Other adverse effects are substantial and will be included. Liability for medical malpractice is of critical importance for the mental health professionals who make the majority of the diagnoses of schizophrenia. The concept put forward in this work will have a discipline-altering impact.
Lake
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Chapter 1: Overview.- Chapter 2: The Basic Data.- Chapter 3: A History of the Diagnoses of Psychotic Patients Before 1950.- Chapter 4: Psychiatric Disease and Diagnoses: The Scientific Basis for Establishing Validity.- Chapter 5: Emil Kraepelin (1856–1926) Established the Kraepelinian Dichotomy and Schizophrenia But Then Reneged.- Chapter 6: Eugene Bleuler (1857-1939) Named and Dedicated Himself to Schizophrenia.- Chapter 7: Jacob Kasanin (1897-1946) and Schizoaffective Disorder.- Chapter 8: Kurt Schneider (1887-1967): First- and Second-Rank Symptoms, Not Pathognomonic of Schizophrenia, Explained by Psychotic Mood Disorders.- Chapter 9: Concepts of Schizophrenia and Bipolar Disorders in the 1950’s and 1960’s.- Chapter 10: Changing Concepts in the 1970’s and 1980’s; The Overlap of Symptoms and Course Between Schizophrenia and Psychotic Mood Disorders.- Chapter 11: Changing Concepts in the 1990’s, 2000’s and 2010’s; More Overlap and Similarities.- Chapter 12: The Subtypes and The Positive and Negative Diagnostic Symptoms of Schizophrenia Are Explained by Psychotic Mood Disorders.- Chapter 13: Psychotic Mood Disorders are Disorders of Thought and of Mood.
C. Raymond Lake, M.D., Ph.D., began his research career in biological psychiatry at the NIMH and published data papers on patients diagnosed with schizophrenia. Dr. Lake is currently a professor of Psychiatry at the University of Kansas, School of Medicine, in Kansas City, Kansas. His expertise includes Psychoneuropharmacology and bipolar disorder. He has published several pieces recently concluding there is only one disorder, a psychotic mood disorder, which accounts for a patient’s functional psychoses.
