Shahi Role of Signaling Pathways in Brain Tumoriogenesis
Buch, Englisch,
Gebunden, Book w. online files / update, Format (B × H): 155 mm x 235 mm
1. Auflage 2021,
Gebunden, Book w. online files / update, Format (B × H): 155 mm x 235 mm
ISBN: 978-981-1584-72-5
Verlag: Springer, Berlin
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Shahi, Mehdi Hayat
Dr. Mehdi Hayat Shahi is an Assistant Professor at the Interdisciplinary Brain Research Centre, Aligarh Muslim University, Aligarh. Before joining AMU, he was a postdoctoral fellow at University of California, Davis, USA from 2010-2014. He was also an instructor at the University California Davis besides his postdoctoral research. From 2009-2010, he worked as a postdoctoral research fellow at Uppsala University, Uppsala, Sweden. His current research interests are focused on molecular neuro-oncology. Towards this pursuit, he is exploring the early stem cell biomarkers that can be utilized for the early diagnosis of brain tumours and other neurodegenerative diseases. He has been honored with many prestigious awards notably, Farah Deeba Award from the Indian Academy of Biomedical Sciences for an outstanding researcher in biomedical sciences, Outstanding Scientist Award for Neuro-oncology research from the Venus International Foundation. He has also served as a referee for the number of international journals, including, PLoS One and Tumour Biology. He has 12 years of research experience in molecular brain tumour biology and 4 years of teaching experience.He has published more than 21 research articles in the peer-reviewed international journals and co-authored two book chapters. He has served as a Co-chair of the Post-doctoral Scholar Association, University of California, USA, from 2013-2014. He is a member of many International Scientific Societies and Organizations importantly International Society for Neurochemistry, Indian Academy of Neurosciences, Indian Association for Cancer Research, and Indian Academy of Biomedical Sciences.
Module 1_Foreword.- Module 2_Preface.- Module 3_Brain Tumours.- Chapter 1. Introduction of brain tumors, Origin and growth.- Chapter 2. Classification of brain tumors from classical to molecular.- Module 4. Cell signalling pathways.- Chapter 3. Introduction of cell signalling pathways.- Chapter 4. Types of Cell signalling pathways and their roles in the brain development. Module 5_Cell signalling pathways. Chapter 5. Sonic hedgehog (Shh) signalling pathway roles in glioma development.- Chapter 6. Potential role of Shh-Glil signalling pathway in medulloblastoma.- Chapter 7. Role of novel transcription factors Nanog, Sox and BMI1 in brain tumoriogeneis.- Chapter 8. Role transcription factors NF-kb, Myc, HIF-1 and Pax6 in brain tumor development.- Chapter 9. Role of neurotrophins cell signalling in brain tumor development.- Chapter 10. Notch cell signalling pathway contribution in brain tumoriogenesis.- Chapter 11. Role of morphogenes Retinoic acid, TGF-b, bone morphogenic factors and Wnt /beta catenine contribution in brain tumor progression.- Module 6_ Cell signalling pathways transcription factors as therapeutic targets and stem Cell.- Chapter12. Role Brain Tumor stem cells in brain tumoriogenesis and potential therapeutic targets.- Chapter 13. Potential molecular markers for the brain tumors therapy. Module 7. Index.- Module 8. Bibliography.- Module 9. Glossary
Shahi, Mehdi Hayat
Dr. Mehdi Hayat Shahi is an Assistant Professor at the Interdisciplinary Brain Research Centre, Aligarh Muslim University, Aligarh. Before joining AMU, he was a postdoctoral fellow at University of California, Davis, USA from 2010-2014. He was also an instructor at the University California Davis besides his postdoctoral research. From 2009-2010, he worked as a postdoctoral research fellow at Uppsala University, Uppsala, Sweden. His current research interests are focused on molecular neuro-oncology. Towards this pursuit, he is exploring the early stem cell biomarkers that can be utilized for the early diagnosis of brain tumours and other neurodegenerative diseases. He has been honored with many prestigious awards notably, Farah Deeba Award from the Indian Academy of Biomedical Sciences for an outstanding researcher in biomedical sciences, Outstanding Scientist Award for Neuro-oncology research from the Venus International Foundation. He has also served as a referee for the number of international journals, including, PLoS One and Tumour Biology. He has 12 years of research experience in molecular brain tumour biology and 4 years of teaching experience.He has published more than 21 research articles in the peer-reviewed international journals and co-authored two book chapters. He has served as a Co-chair of the Post-doctoral Scholar Association, University of California, USA, from 2013-2014. He is a member of many International Scientific Societies and Organizations importantly International Society for Neurochemistry, Indian Academy of Neurosciences, Indian Association for Cancer Research, and Indian Academy of Biomedical Sciences.
Module 1_Foreword.- Module 2_Preface.- Module 3_Brain Tumours.- Chapter 1. Introduction of brain tumors, Origin and growth.- Chapter 2. Classification of brain tumors from classical to molecular.- Module 4. Cell signalling pathways.- Chapter 3. Introduction of cell signalling pathways.- Chapter 4. Types of Cell signalling pathways and their roles in the brain development. Module 5_Cell signalling pathways. Chapter 5. Sonic hedgehog (Shh) signalling pathway roles in glioma development.- Chapter 6. Potential role of Shh-Glil signalling pathway in medulloblastoma.- Chapter 7. Role of novel transcription factors Nanog, Sox and BMI1 in brain tumoriogeneis.- Chapter 8. Role transcription factors NF-kb, Myc, HIF-1 and Pax6 in brain tumor development.- Chapter 9. Role of neurotrophins cell signalling in brain tumor development.- Chapter 10. Notch cell signalling pathway contribution in brain tumoriogenesis.- Chapter 11. Role of morphogenes Retinoic acid, TGF-b, bone morphogenic factors and Wnt /beta catenine contribution in brain tumor progression.- Module 6_ Cell signalling pathways transcription factors as therapeutic targets and stem Cell.- Chapter12. Role Brain Tumor stem cells in brain tumoriogenesis and potential therapeutic targets.- Chapter 13. Potential molecular markers for the brain tumors therapy. Module 7. Index.- Module 8. Bibliography.- Module 9. Glossary
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