Familial Mediterranean Fever (Fmf)

Erscheinungsjahr 2020
ISBN: 978-0-12-821832-7
Verlag: Elsevier Science

Buch, Englisch, 160 Seiten, Format (B × H): 156 mm x 234 mm

Familial Mediterranean Fever (FMF) is one of the most common genetic diseases in the world with more than 500,000 patients. Most are concentrated in Turkey, Israel, Armenia and other countries in the Mediterranean basin, however due to population migration FMF patients have been identified virtually in every country around the globe. With the increasing awareness of FMF and other autoinflammatory diseases in a wider geography, information concerning new disease associations, genotype-phenotype relations, effect of environmental factors, new treatment modalities, and recent advances in the pathogenesis have been accumulated. After being diagnosed with the disease, a disease for life, patients are left with many questions regarding their disease. This book encompasses all possible aspects of the disease, symptoms, clinical and genetic diagnosis, treatment, complications as well as a personal point of view from the patient's side in coping with the disease. The book is detailed and comprehensive so that it could also be a great value for medical staff, physicians and nurses interested in learning more details about the disease.



- Provides answers by medical experts to critical real world questions
- Gives an overview and an update on FMF
- Shows that FMF is not restricted to Mediterranean countries, and the lack of diagnosis in other areas of the world is probably due to a lack of awareness of this fascinating disease
- Raises the awareness of physicians regarding this disease so that patients can obtain the correct diagnosis and receive the appropriate treatment

Zielgruppe

<p>Academies, Institutes of research, Foundations involved in rare diseases, medical doctors and their patients </p> <p>Commercial companies manufacturing new treatment for FMF, Novartis, Boehringer Ingelheim Pharma, Kiniksa Pharmaceuticals/Regenerong </p>

Autoren/Hrsg.

Shoenfeld, Yehuda

Pras, Elon

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Infektionskrankheiten

Inhaltsverzeichnis

1. Historic perspectives in FMF
2. Epidemiology and ethnic distribution
3. Clinical features of FMF
4. Amyloidosis in FMF
5. Differential diagnosis of FMF
6. Colchicine treatment in FMF
7. Anti interleukin 1 treatment in FMF
8. Medical follow up for FMF patients
9. FMF in children
10. The genetics of FMF
11. Accompanying diseases in FMF
12. FMF and the kidney
13. Fibromyalgia in FMF
14. Protracted Febrile Myalgia in FMF
15. Fertility issues in FMF
16. Long term prognosis in FMF
17. Living with FMF
18. The work market for patients with FMF
19. Questions and answers

Über Autor(innen)

Shoenfeld, Yehuda
President of the Center for Autoimmune diseases (Present). Incumbent of the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases in Tel-Aviv University (since 2002 - Present). Emeritus Professor of the Sackler School of Medicine in Tel-Aviv University, and teaches medical studies and MSc, & PhD students (since 1985). Prof. Shoenfeld edited series of Textbooks entailing "The Mosaic of Autoimmunity", Textbook on "Autoantibodies", "Infection and autoimmunity", and "Diagnostic criteria of Autoimmune Diseases".(Elsevier Pub.) On 36 Editorial Boards, and the organizer of more than 25 international congresses on Autoimmunity. Author of > 2000 peer review papers reported in the field of autoimmunity and internal medicine. More than 65,000 citations.

Pras, Elon
Prof. Elon Pras, MD, PhD Genetics Research serves as an Associate Professor at the Sackler School of Medicine, Tel Aviv University and is actively involved in teaching medical, MSc and PhD students. Prof. Pras serves as a Member of Scientific Advisory Board of PsoriasisDX, LLC; DermaGenoma,;Inc and HairDX, LLC. He is the Director of the Institute of Human Genetics at the Sheva Medical Center, Israel. The Institute is the largest of its kind in the Middle East and it performs thousands of clinical diagnostic genetic testing each month. The Institute is also highly dedicated to science and research. After completing residency in internal medicine, he joined a four year a fellowship program in rheumatology and molecular genetics at the National Institutes of Health. He continued with a second fellowship in clinical genetics which he finished in 2001. Prof. Pras is an expert in positional cloning, a technique which is used to identify genes that cause genetic diseases. During the last 10 years, he was involved in the identification of the genes that cause familial Mediterranean fever, cystinuria, cardiac arrhythmias, familial cataract, autosomal dominant hypotrichosis simplex and autosomal recessive monilethrix. Prof. Pras is graduated from medical school at the Beer Sheba University in 1985. He has Ph.D in Genetics Research