Designed to supplement existing organic textbooks, Hybrid Retrosynthesis presents a relatively simple approach to solving synthesis problems, using a small library of basic reactions along with the computer searching capabilities of Reaxys and SciFinder. This clear, concise guide reviews the essential skills needed for organic synthesis and retrosynthesis, expanding reader knowledge of the foundational principles of these techniques, whilst supporting their use via practical methodologies. Perfect for both graduate and post-graduate students, Hybrid Retrosynthesis provides new applied skills and tools to help during their organic synthesis courses and future careers, whilst simultaneously acting as useful resource for those setting tutorial and group problems, and as a helpful go-to guide for organic chemists involved in either industry or academia. - Ideal revision and hands on learning guide for organic synthesis - Clearly explains the principles and practice of retrosynthesis, which is often not covered in other books - Encourages readers to practice their synthetic knowledge supported by real life examples
Michael B. Smith, University of Connecticut, is a world renowned author of leading organic textbooks.
Smith / D'Angelo
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Weitere Infos & Material
Summary of Reactions in Chapter 8
| 01. | From Aldehydes or Ketones | |
| 02. | From Carboxylic Acids | |
| 03. | From Acid Derivatives (acid chlorides, anhydrides, esters) | |
| 06. | From Ketones or Aldehydes | |
| ALCOHOL-ALCOHOL. See DIOLS | 85 |
| ALCOHOLS-FUNCTIONALIZED | 85 |
| 07. | From Epoxides or Alkenes | |
| 16. | From Ketones or Aldehydes | |
| 18. | From Halides, Sulfonate Esters, or Ammonium Salts | |
| ALKYL HALIDES: See HALIDES, ALKYL | 95 |
| 20. | From Acid Derivatives | |
| 22. | From Azides, Imides, and Halides | |
| 25. | From Carboxylic Acids and Acid Derivatives | |
| ARYL HALIDES: See HALIDES, ARYL | 101 |
| 26. | From Acid Derivatives (Acid chlorides, Anhydrides, Esters, Amides) | |
| 28. | From 1,3-Dicarboxylic Acids | |
| DIHALIDES. See Halides | 106 |
| 33. | From Ketones or Aldehydes | |
| 36. | From Carboxylic Acids and Acids Derivatives | |
| 40. | From Alkanes and Aryls | |
| 44. | From Ketones or Aldehydes | |
| KETONES or ALDEHYDES. See ALDEHYDES | 119 |
| 54. | From Acid Derivatives and Organometallics | |
| 56. | From Ketones or Aldehydes and Organometallics | |
| ALCOHOL-KETONES. See KETONE-ALCOHOL | 129 |
| ALDEHYDES and KETONES | 129 |
| 58. | From Aldehydes or Ketones and Alkyl Halides | |
| 59. | From Organometallics and Dimethylformamide (DMF) | |
| 60. | From Allylic Vinyl Ethers | |
| 62. | From Alkyl Halides and Organometallics | |
| 63. | From Alkenes and Aryl Halides (Heck reaction) | |
| 64. | From Alkenes and Dienes | |
| 66. | From Ketones or Aldehydes and Ylids | |
| 67. | From Alkyne Anions and Alkyl Halides (SN2 Reaction) or Aryl... |
