Srivastava / Anand-Srivastava Signal Transduction in the Cardiovascular System in Health and Disease

1. Auflage 2008
ISBN: 978-0-387-09552-3
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 3, 424 Seiten

Reihe: Advances in Biochemistry in Health and Disease

Signal Transduction in Cardiovascular System Health and Disease highlights the major contributions of different signaling systems in modulating normal cardiovascular functions and how a perturbation in these signaling events leads to abnormal cell functions and cardiovascular disorders. This title is volume 3 in the new Springer series, Advances in Biochemistry in Health and Disease.

Autoren/Hrsg.

Srivastava, Ashok K.

Anand-Srivastava, Madhu B.

Inhaltsverzeichnis

1;Preface;6
2;Contents;9
3;Contributors;12
4;Part I G-protein-Coupled Receptor Signaling;18
4.1;Chapter 1 Implication of G-proteins in Cardiovascular Disease;19
4.2;Chapter 2 ß-Adrenoceptor-Linked Signal Transduction Mechanisms in Congestive Heart Failure;43
4.3;Chapter 3 Cardiac G as and G ai Modulate Sympathetic Versus Parasympathetic Mechanisms in Hyperhomocysteinemia;66
4.4;Chapter 4 The Role of the Beta-Adrenergic Signal Transduction Pathway in Myocardial Protection;82
4.5;Chapter 5 Angiotensin II Signaling in Vascular Physiology and Pathophysiology;103
4.6;Chapter 6 Angiotensin II Signaling: Cell Growth and Apoptosis;130
5;Part II Redox Signaling;151
5.1;Chapter 7 Thioredoxin Signaling in the Ischemic Heart;152
5.2;Chapter 8 Relationship Between Redox Regulation and ß-Adrenergic Responses in the Heart;167
5.3;Chapter 9 Role of Hyperglycemia and Redox-Induced Signaling in Vascular Complications of Diabetes;187
5.4;Chapter 10 Methylglyoxal and Insulin Resistance;203
6;Part III Growth Factor Signaling;219
6.1;Chapter 11 Role of Growth Factor Receptor Transactivation in Vasoactive Peptide-Induced Signaling Pathways in Vascular Smooth Muscle Cells;220
6.2;Chapter 12 Identifying the Cellular and Molecular Events Associated with the Divergent Phenotypes of Cardiac Hypertrophy;238
6.3;Chapter 13 Regulatory Role of TGF-ß in Cardiac Myofibroblast Function and Post-MI Cardiac Fibrosis: Key Roles of Smad7 and c-Ski;257
6.4;Chapter 14 The Signaling Duel Between Virus and Host: Impact on Coxsackieviral Pathogenesis;275
6.5;Chapter 15 Therapeutic Angiogenesis and Vasculogenesis for Ischemic Disease;293
6.6;Chapter 16 VEGF Signaling: A Therapeutic Target for Cardiovascular Disease;308
6.7;Chapter 17 Myristoyl-CoA: Protein N-Myristoyltransferase and Myristoyl-CoA Binding Protein from Bovine Cardiac Muscle;334
7;Part IV Calcium Signaling;343
7.1;Chapter 18 Ca2+ / Calmodulin-Dependent Protein Kinase II Signaling in Vascular Smooth Muscle;344
7.2;Chapter 19 The KCa3.1 Channel in Endothelial Cells as New Target for an EDHF-Based Control of Vascular Tone: From Structure to Regulation and Pharmacological Properties;361
8;Part V Adipokine Signaling;379
8.1;Chapter 20 Leptin Signaling in the Cardiovascular System;380
8.2;Chapter 21 AMPK Regulation of Cardiac Metabolism in Heart Disease;399
8.3;Signal Transduction in the Cardiovascular System in Health and Disease;413
9;Index;415